Mucoadhesive PLGA Nanospheres and Nanocapsules for Lactoferrin Controlled Ocular Delivery

Mucoadhesive PLGA Nanospheres and Nanocapsules for Lactoferrin Controlled Ocular Delivery

Background: the present work describes the preparation, characterization and optimization of eight types of PLGA-based nanosystems (nanospheres and nanocapsules) as innovative mucoadhesive drug delivery systems of lactoferrin, in order to achieve a preclinical consistent base as an alternative pharm...

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Bibliographic Details
Main Authors: Rubén Varela-Fernández, Xurxo García-Otero, Victoria Díaz-Tomé, Uxía Regueiro, Maite López-López, Miguel González-Barcia, María Isabel Lema, Francisco Javier Otero-Espinar
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceutics
Subjects:
nanoparticles
PLGA
lactoferrin
topical ophthalmic administration
nanoprecipitation
protein nanocarriers
Online Access:https://www.mdpi.com/1999-4923/14/4/799

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