Phytochemical Profiling and Biological Activities of <i>Rhododendron</i> Subsect. <i>Ledum</i>: Discovering the Medicinal Potential of Labrador Tea Species in the Northern Hemisphere
<i>Rhododendron</i> subsect. <i>Ledum</i> is a distinct taxonomic subdivision within the genus <i>Rhododendron</i>, comprising a group of evergreen shrubs and small trees. This review will comprehensively analyse the phytochemical profiles and biological propertie...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | Plants |
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| Online Access: | https://www.mdpi.com/2223-7747/13/6/901 |
| _version_ | 1797239612300591104 |
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| author | Martyna Vengrytė Lina Raudonė |
| author_facet | Martyna Vengrytė Lina Raudonė |
| author_sort | Martyna Vengrytė |
| collection | DOAJ |
| description | <i>Rhododendron</i> subsect. <i>Ledum</i> is a distinct taxonomic subdivision within the genus <i>Rhododendron</i>, comprising a group of evergreen shrubs and small trees. This review will comprehensively analyse the phytochemical profiles and biological properties of the <i>Rhododendron</i> subsect. <i>Ledum</i> species subsect. <i>Ledum</i> consists of eight plant species indigenous to temperate and subarctic regions of the Northern Hemisphere, collectively known as Labrador tea. Recent investigations have concentrated on the phytochemical constituents of these plants due to limited data, emphasizing their evergreen nature and potential industrial significance. This review summarizes their major phytochemical constituents, including flavonoids, phenolic acids, and terpenoids, and discusses their potential biological activities, such as antioxidant, anti-inflammatory, antimicrobial, antitumor, hypoglycemic, hepatoprotective, neuroprotective, and cardioprotective effects. Traditional uses of these plant species align with scientific findings, emphasizing the significance of these plants in traditional medicine. However, despite promising results, gaps exist in our understanding of specific compounds’ therapeutic effects, necessitating further research for comprehensive validation. This review serves as a valuable resource for researchers, identifying current knowledge, uncertainties, and emerging trends in the study of the <i>Rhododendron</i> subsect. <i>Ledum</i> species. |
| first_indexed | 2024-04-24T17:54:18Z |
| format | Article |
| id | doaj.art-ed10634516164049a5392e120cac52fa |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-04-24T17:54:18Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-ed10634516164049a5392e120cac52fa2024-03-27T14:01:00ZengMDPI AGPlants2223-77472024-03-0113690110.3390/plants13060901Phytochemical Profiling and Biological Activities of <i>Rhododendron</i> Subsect. <i>Ledum</i>: Discovering the Medicinal Potential of Labrador Tea Species in the Northern HemisphereMartyna Vengrytė0Lina Raudonė1Laboratory of Biopharmaceutical Research, Institute of Pharmaceutical Technologies, Lithuanian University of Health Sciences, Sukileliu Av. 13, LT-50162 Kaunas, LithuaniaLaboratory of Biopharmaceutical Research, Institute of Pharmaceutical Technologies, Lithuanian University of Health Sciences, Sukileliu Av. 13, LT-50162 Kaunas, Lithuania<i>Rhododendron</i> subsect. <i>Ledum</i> is a distinct taxonomic subdivision within the genus <i>Rhododendron</i>, comprising a group of evergreen shrubs and small trees. This review will comprehensively analyse the phytochemical profiles and biological properties of the <i>Rhododendron</i> subsect. <i>Ledum</i> species subsect. <i>Ledum</i> consists of eight plant species indigenous to temperate and subarctic regions of the Northern Hemisphere, collectively known as Labrador tea. Recent investigations have concentrated on the phytochemical constituents of these plants due to limited data, emphasizing their evergreen nature and potential industrial significance. This review summarizes their major phytochemical constituents, including flavonoids, phenolic acids, and terpenoids, and discusses their potential biological activities, such as antioxidant, anti-inflammatory, antimicrobial, antitumor, hypoglycemic, hepatoprotective, neuroprotective, and cardioprotective effects. Traditional uses of these plant species align with scientific findings, emphasizing the significance of these plants in traditional medicine. However, despite promising results, gaps exist in our understanding of specific compounds’ therapeutic effects, necessitating further research for comprehensive validation. This review serves as a valuable resource for researchers, identifying current knowledge, uncertainties, and emerging trends in the study of the <i>Rhododendron</i> subsect. <i>Ledum</i> species.https://www.mdpi.com/2223-7747/13/6/901<i>Rhododendron</i><i>Ledum</i>phytochemicalEricaceaepharmacology |
| spellingShingle | Martyna Vengrytė Lina Raudonė Phytochemical Profiling and Biological Activities of <i>Rhododendron</i> Subsect. <i>Ledum</i>: Discovering the Medicinal Potential of Labrador Tea Species in the Northern Hemisphere Plants <i>Rhododendron</i> <i>Ledum</i> phytochemical Ericaceae pharmacology |
| title | Phytochemical Profiling and Biological Activities of <i>Rhododendron</i> Subsect. <i>Ledum</i>: Discovering the Medicinal Potential of Labrador Tea Species in the Northern Hemisphere |
| title_full | Phytochemical Profiling and Biological Activities of <i>Rhododendron</i> Subsect. <i>Ledum</i>: Discovering the Medicinal Potential of Labrador Tea Species in the Northern Hemisphere |
| title_fullStr | Phytochemical Profiling and Biological Activities of <i>Rhododendron</i> Subsect. <i>Ledum</i>: Discovering the Medicinal Potential of Labrador Tea Species in the Northern Hemisphere |
| title_full_unstemmed | Phytochemical Profiling and Biological Activities of <i>Rhododendron</i> Subsect. <i>Ledum</i>: Discovering the Medicinal Potential of Labrador Tea Species in the Northern Hemisphere |
| title_short | Phytochemical Profiling and Biological Activities of <i>Rhododendron</i> Subsect. <i>Ledum</i>: Discovering the Medicinal Potential of Labrador Tea Species in the Northern Hemisphere |
| title_sort | phytochemical profiling and biological activities of i rhododendron i subsect i ledum i discovering the medicinal potential of labrador tea species in the northern hemisphere |
| topic | <i>Rhododendron</i> <i>Ledum</i> phytochemical Ericaceae pharmacology |
| url | https://www.mdpi.com/2223-7747/13/6/901 |
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