Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-<sub>XL </sub>expression

Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-<sub>XL </sub>expression

<p>Abstract</p> <p>Background</p> <p>Thymoquinone (TQ), the major active component of the medicinal herb Nigella sativa Linn., has been described as a chemopreventive and chemotherapeutic compound.</p> <p>Methods</p> <p>In this study, we investig...

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Bibliographic Details
Main Authors: Badr Gamal, Mohany Mohamed, Abu-Tarboush Faisal
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Lipids in Health and Disease
Subjects:
Cytoskeleton
multiple myeloma
proliferation
signaling
thymoquinone
Online Access:http://www.lipidworld.com/content/10/1/236

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