Decreased ex vivo production of interferon-gamma is associated with severity and poor prognosis in patients with lupus

Decreased ex vivo production of interferon-gamma is associated with severity and poor prognosis in patients with lupus

Abstract Background Lupus pathogenesis is closely associated with interferon gamma (IFN-γ), which plays a central role in innate and adaptive immunity. The aim of this study was to evaluate the ex vivo production of IFN-γ after stimulation of peripheral blood mononuclear cells with phytohemagglutini...

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Bibliographic Details
Main Authors: Sung Soo Ahn, Eun Seong Park, Joo Sung Shim, Sang-Jun Ha, Beom Seok Kim, Seung Min Jung, Sang-Won Lee, Yong-Beom Park, Jason Jungsik Song
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Arthritis Research & Therapy
Subjects:
IFN-γ releasing assay
IFN-γ
Systemic lupus erythematosus
T cell
Online Access:http://link.springer.com/article/10.1186/s13075-017-1404-z

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