Intracellular Transport of Viruses and Their Components: Utilizing the Cytoskeleton and Membrane Highways
Plant viruses are obligate organisms that require host components for movement within and between cells. A mechanistic understanding of virus movement will allow the identification of new methods to control virus systemic spread and serve as a model system for understanding host macromolecule intra-...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The American Phytopathological Society
2010-11-01
|
| Series: | Molecular Plant-Microbe Interactions |
| Online Access: | https://apsjournals.apsnet.org/doi/10.1094/MPMI-05-10-0121 |
| _version_ | 1811261271208624128 |
|---|---|
| author | Phillip A. Harries James E. Schoelz Richard S. Nelson |
| author_facet | Phillip A. Harries James E. Schoelz Richard S. Nelson |
| author_sort | Phillip A. Harries |
| collection | DOAJ |
| description | Plant viruses are obligate organisms that require host components for movement within and between cells. A mechanistic understanding of virus movement will allow the identification of new methods to control virus systemic spread and serve as a model system for understanding host macromolecule intra- and intercellular transport. Recent studies have moved beyond the identification of virus proteins involved in virus movement and their effect on plasmodesmal size exclusion limits to the analysis of their interactions with host components to allow movement within and between cells. It is clear that individual virus proteins and replication complexes associate with and, in some cases, traffic along the host cytoskeleton and membranes. Here, we review these recent findings, highlighting the diverse associations observed between these components and their trafficking capacity. Plant viruses operate individually, sometimes within virus species, to utilize unique interactions between their proteins or complexes and individual host cytoskeletal or membrane elements over time or space for their movement. However, there is not sufficient information for any plant virus to create a complete model of its intracellular movement; thus, more research is needed to achieve that goal. |
| first_indexed | 2024-04-12T19:00:19Z |
| format | Article |
| id | doaj.art-ed17f9a6efb04e6a92acb051d20522e2 |
| institution | Directory Open Access Journal |
| issn | 0894-0282 1943-7706 |
| language | English |
| last_indexed | 2024-04-12T19:00:19Z |
| publishDate | 2010-11-01 |
| publisher | The American Phytopathological Society |
| record_format | Article |
| series | Molecular Plant-Microbe Interactions |
| spelling | doaj.art-ed17f9a6efb04e6a92acb051d20522e22022-12-22T03:20:11ZengThe American Phytopathological SocietyMolecular Plant-Microbe Interactions0894-02821943-77062010-11-0123111381139310.1094/MPMI-05-10-0121Intracellular Transport of Viruses and Their Components: Utilizing the Cytoskeleton and Membrane HighwaysPhillip A. HarriesJames E. SchoelzRichard S. NelsonPlant viruses are obligate organisms that require host components for movement within and between cells. A mechanistic understanding of virus movement will allow the identification of new methods to control virus systemic spread and serve as a model system for understanding host macromolecule intra- and intercellular transport. Recent studies have moved beyond the identification of virus proteins involved in virus movement and their effect on plasmodesmal size exclusion limits to the analysis of their interactions with host components to allow movement within and between cells. It is clear that individual virus proteins and replication complexes associate with and, in some cases, traffic along the host cytoskeleton and membranes. Here, we review these recent findings, highlighting the diverse associations observed between these components and their trafficking capacity. Plant viruses operate individually, sometimes within virus species, to utilize unique interactions between their proteins or complexes and individual host cytoskeletal or membrane elements over time or space for their movement. However, there is not sufficient information for any plant virus to create a complete model of its intracellular movement; thus, more research is needed to achieve that goal.https://apsjournals.apsnet.org/doi/10.1094/MPMI-05-10-0121 |
| spellingShingle | Phillip A. Harries James E. Schoelz Richard S. Nelson Intracellular Transport of Viruses and Their Components: Utilizing the Cytoskeleton and Membrane Highways Molecular Plant-Microbe Interactions |
| title | Intracellular Transport of Viruses and Their Components: Utilizing the Cytoskeleton and Membrane Highways |
| title_full | Intracellular Transport of Viruses and Their Components: Utilizing the Cytoskeleton and Membrane Highways |
| title_fullStr | Intracellular Transport of Viruses and Their Components: Utilizing the Cytoskeleton and Membrane Highways |
| title_full_unstemmed | Intracellular Transport of Viruses and Their Components: Utilizing the Cytoskeleton and Membrane Highways |
| title_short | Intracellular Transport of Viruses and Their Components: Utilizing the Cytoskeleton and Membrane Highways |
| title_sort | intracellular transport of viruses and their components utilizing the cytoskeleton and membrane highways |
| url | https://apsjournals.apsnet.org/doi/10.1094/MPMI-05-10-0121 |
| work_keys_str_mv | AT phillipaharries intracellulartransportofvirusesandtheircomponentsutilizingthecytoskeletonandmembranehighways AT jameseschoelz intracellulartransportofvirusesandtheircomponentsutilizingthecytoskeletonandmembranehighways AT richardsnelson intracellulartransportofvirusesandtheircomponentsutilizingthecytoskeletonandmembranehighways |