BKCa channel dysfunction in neurological diseases

The large conductance, Ca2+-activated K+ channels (BKCa, KCa1.1) are expressed in various brain neurons where they play important roles in regulating action potential duration, firing frequency and neurotransmitter release. Membrane potential depolarization and rising levels of intracellular Ca2+ ga...

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Bibliographic Details
Main Author: Prosper eN'Gouemo
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00373/full

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