Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and Future
Sensitive and rapid label-free biological and chemical sensors are needed for a wide variety of applications including early disease diagnosis and prognosis, the monitoring of food and water quality, as well as the detection of bacteria and viruses for public health concerns and chemical threat sens...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-03-01
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| Series: | Sensors |
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| Online Access: | http://www.mdpi.com/1424-8220/17/3/540 |
| _version_ | 1828153094127484928 |
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| author | Judith Su |
| author_facet | Judith Su |
| author_sort | Judith Su |
| collection | DOAJ |
| description | Sensitive and rapid label-free biological and chemical sensors are needed for a wide variety of applications including early disease diagnosis and prognosis, the monitoring of food and water quality, as well as the detection of bacteria and viruses for public health concerns and chemical threat sensing. Whispering gallery mode optical resonator based sensing is a rapidly developing field due to the high sensitivity and speed of these devices as well as their label-free nature. Here, we describe the history of whispering gallery mode optical resonator sensors, the principles behind detection, the latest developments in the fields of biological and chemical sensing, current challenges toward widespread adoption of these devices, and an outlook for the future. In addition, we evaluate the performance capabilities of these sensors across three key parameters: sensitivity, selectivity, and speed. |
| first_indexed | 2024-04-11T22:20:33Z |
| format | Article |
| id | doaj.art-ed19275709e1454cbc55add064ae0603 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-11T22:20:33Z |
| publishDate | 2017-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-ed19275709e1454cbc55add064ae06032022-12-22T04:00:10ZengMDPI AGSensors1424-82202017-03-0117354010.3390/s17030540s17030540Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and FutureJudith Su0College of Optical Sciences, Department of Chemistry & Biochemistry, University of Arizona Cancer Center, University of Arizona, Tucson, AZ 85721, USASensitive and rapid label-free biological and chemical sensors are needed for a wide variety of applications including early disease diagnosis and prognosis, the monitoring of food and water quality, as well as the detection of bacteria and viruses for public health concerns and chemical threat sensing. Whispering gallery mode optical resonator based sensing is a rapidly developing field due to the high sensitivity and speed of these devices as well as their label-free nature. Here, we describe the history of whispering gallery mode optical resonator sensors, the principles behind detection, the latest developments in the fields of biological and chemical sensing, current challenges toward widespread adoption of these devices, and an outlook for the future. In addition, we evaluate the performance capabilities of these sensors across three key parameters: sensitivity, selectivity, and speed.http://www.mdpi.com/1424-8220/17/3/540label-freebiosensingchemical sensingoptical resonatorsingle moleculemicrocavitywhispering gallery mode |
| spellingShingle | Judith Su Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and Future Sensors label-free biosensing chemical sensing optical resonator single molecule microcavity whispering gallery mode |
| title | Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and Future |
| title_full | Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and Future |
| title_fullStr | Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and Future |
| title_full_unstemmed | Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and Future |
| title_short | Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and Future |
| title_sort | label free biological and chemical sensing using whispering gallery mode optical resonators past present and future |
| topic | label-free biosensing chemical sensing optical resonator single molecule microcavity whispering gallery mode |
| url | http://www.mdpi.com/1424-8220/17/3/540 |
| work_keys_str_mv | AT judithsu labelfreebiologicalandchemicalsensingusingwhisperinggallerymodeopticalresonatorspastpresentandfuture |