Hyperbaric oxygen augments susceptibility to C. difficile infection by impairing gut microbiota ability to stimulate the HIF-1α-IL-22 axis in ILC3

Hyperbaric oxygen augments susceptibility to C. difficile infection by impairing gut microbiota ability to stimulate the HIF-1α-IL-22 axis in ILC3

ABSTRACTHyperbaric oxygen (HBO) therapy is a well-established method for improving tissue oxygenation and is typically used for the treatment of various inflammatory conditions, including infectious diseases. However, its effect on the intestinal mucosa, a microenvironment known to be physiologicall...

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Bibliographic Details
Main Authors: José L. Fachi, Laís. P. Pral, Helder C. Assis, Sarah Oliveira, Vinícius R. Rodovalho, Jefferson A. C. dos Santos, Mariane F. Fernandes, Valquíria A. Matheus, Renata Sesti-Costa, Paulo J. Basso, Marina Flóro e Silva, Niels O. S. Câmara, Selma Giorgio, Marco Colonna, Marco A. R. Vinolo
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Gut Microbes
Subjects:
Hyperbaric oxygen
microbiota
butyrate
clostridioides difficile
innate lymphoid cells
ILC3
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2297872

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