| Summary: | Angiomyomatous hamartoma is a rare disease of the lymph nodes, particularly inguinal and femoral lymph nodes. It was first identified as a distinct entity by Chan et al. in 1992. Histologically, it is characterized by the replacement of lymph nodal parenchyma with irregularly distributed thick-walled variable-sized blood vessels, haphazardly arranged smooth muscle cells, and variable amounts of fat and fibrous tissue in a sclerotic lymphatic stroma. Only a few atrophic lymphatic follicles are seen in the subcapsular area. The exact pathogenesis is still controversial. Although this entity is very rare, its recognition is important in discriminating it from other benign and malignant vascular lesions of lymph nodes.
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