Nitric oxide synthase inhibitors protect cholinergic neurons against quinolinic acid toxicity in the rat brain

Nitric oxide synthase inhibitors protect cholinergic neurons against quinolinic acid toxicity in the rat brain

The aim of this study was to examine the effects of intrastriatally injected nitric oxide synthase (NOS) inhibitors, Nω-nitro-l-arginine methyl ester (L-NAME) and 7-nitroindazole (7-NI), on quinolinic acid (QA)-induced toxicity in selective vulnerable brain regions of adult Wistar rats. QA was a...

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Bibliographic Details
Main Authors: Stevanović Ivana, Jovanović Marina, Ninković Milica
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2013-01-01
Series:Archives of Biological Sciences
Subjects:
Acetylcholinesterase
Huntington’s disease
quinolinic acid
Nω-nitro-l-arginine methyl ester
7-nitroindazole
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2013/0354-46641302519S.pdf

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