Clozapine: the past, present, and future

Today even after fifty years of its manufacture the decision to use clozapine still represents a challenge to the clinician because of the complexities involved in accurately assessing its risks and benefits. Debate and uncertainty as to what represents an adequate trial, indications, and the mechan...

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Bibliographic Details
Main Authors: Sekh Afrar Alam, Aparajeeta Baruah, Bondana Timungpi
Format: Article
Language:English
Published: Academy Publisher 2015-07-01
Series:Open Journal of Psychiatry and Allied Sciences
Subjects:
Online Access:http://dysphrenia.hpage.co.in/074-082-fulltext_75395976.html
Description
Summary:Today even after fifty years of its manufacture the decision to use clozapine still represents a challenge to the clinician because of the complexities involved in accurately assessing its risks and benefits. Debate and uncertainty as to what represents an adequate trial, indications, and the mechanism of action of clozapine is continuing. The author conducted a review of studies that highlighted its historical aspect, the mechanism of action, efficacy, tolerability, and indications of clozapine in current perspective.
ISSN:2394-2053
2394-2061