Clozapine: the past, present, and future
Today even after fifty years of its manufacture the decision to use clozapine still represents a challenge to the clinician because of the complexities involved in accurately assessing its risks and benefits. Debate and uncertainty as to what represents an adequate trial, indications, and the mechan...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Academy Publisher
2015-07-01
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| Series: | Open Journal of Psychiatry and Allied Sciences |
| Subjects: | |
| Online Access: | http://dysphrenia.hpage.co.in/074-082-fulltext_75395976.html |
| _version_ | 1819110209380941824 |
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| author | Sekh Afrar Alam Aparajeeta Baruah Bondana Timungpi |
| author_facet | Sekh Afrar Alam Aparajeeta Baruah Bondana Timungpi |
| author_sort | Sekh Afrar Alam |
| collection | DOAJ |
| description | Today even after fifty years of its manufacture the decision to use clozapine still represents a challenge to the clinician because of the complexities involved in accurately assessing its risks and benefits. Debate and uncertainty as to what represents an adequate trial, indications, and the mechanism of action of clozapine is continuing. The author conducted a review of studies that highlighted its historical aspect, the mechanism of action, efficacy, tolerability, and indications of clozapine in current perspective. |
| first_indexed | 2024-12-22T03:38:05Z |
| format | Article |
| id | doaj.art-ed2247980c024c9c91e536a21b8d563e |
| institution | Directory Open Access Journal |
| issn | 2394-2053 2394-2061 |
| language | English |
| last_indexed | 2024-12-22T03:38:05Z |
| publishDate | 2015-07-01 |
| publisher | Academy Publisher |
| record_format | Article |
| series | Open Journal of Psychiatry and Allied Sciences |
| spelling | doaj.art-ed2247980c024c9c91e536a21b8d563e2022-12-21T18:40:19ZengAcademy PublisherOpen Journal of Psychiatry and Allied Sciences2394-20532394-20612015-07-01627482Clozapine: the past, present, and futureSekh Afrar Alam0Aparajeeta Baruah1Bondana Timungpi2DPM, MD, Senior Resident, Department of Psychiatry, LGB Regional Institute of Mental Health, Tezpur, Assam, IndiaMD, Professor & Head of Department, Department of Psychiatry, LGB Regional Institute of Mental Health, Tezpur, Assam, IndiaMD, Assistant Professor, LGB Regional Institute of Mental Hhealth, Tezpur, Assam, IndiaToday even after fifty years of its manufacture the decision to use clozapine still represents a challenge to the clinician because of the complexities involved in accurately assessing its risks and benefits. Debate and uncertainty as to what represents an adequate trial, indications, and the mechanism of action of clozapine is continuing. The author conducted a review of studies that highlighted its historical aspect, the mechanism of action, efficacy, tolerability, and indications of clozapine in current perspective.http://dysphrenia.hpage.co.in/074-082-fulltext_75395976.htmlAgranulocytosisSchizophreniaAntipsychotic Agents |
| spellingShingle | Sekh Afrar Alam Aparajeeta Baruah Bondana Timungpi Clozapine: the past, present, and future Open Journal of Psychiatry and Allied Sciences Agranulocytosis Schizophrenia Antipsychotic Agents |
| title | Clozapine: the past, present, and future |
| title_full | Clozapine: the past, present, and future |
| title_fullStr | Clozapine: the past, present, and future |
| title_full_unstemmed | Clozapine: the past, present, and future |
| title_short | Clozapine: the past, present, and future |
| title_sort | clozapine the past present and future |
| topic | Agranulocytosis Schizophrenia Antipsychotic Agents |
| url | http://dysphrenia.hpage.co.in/074-082-fulltext_75395976.html |
| work_keys_str_mv | AT sekhafraralam clozapinethepastpresentandfuture AT aparajeetabaruah clozapinethepastpresentandfuture AT bondanatimungpi clozapinethepastpresentandfuture |