Aging Is a Risk Factor for Utricular Dysfunction in Idiopathic Benign Paroxysmal Positional Vertigo
Benign paroxysmal positional vertigo (BPPV) is the most common cause of balance disorders in the elderly. Dislodgement of the otoconia in BPPV might have an association with damage to the otolith organs. The aim of this study was to investigate whether aging is a risk factor for otolith organ dysfun...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-12-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2018.01049/full |
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| author | Chisato Fujimoto Chisato Fujimoto Takuya Kawahara Makoto Kinoshita Yayoi S. Kikkawa Keiko Sugasawa Masato Yagi Tatsuya Yamasoba Shinichi Iwasaki Toshihisa Murofushi Toshihisa Murofushi |
| author_facet | Chisato Fujimoto Chisato Fujimoto Takuya Kawahara Makoto Kinoshita Yayoi S. Kikkawa Keiko Sugasawa Masato Yagi Tatsuya Yamasoba Shinichi Iwasaki Toshihisa Murofushi Toshihisa Murofushi |
| author_sort | Chisato Fujimoto |
| collection | DOAJ |
| description | Benign paroxysmal positional vertigo (BPPV) is the most common cause of balance disorders in the elderly. Dislodgement of the otoconia in BPPV might have an association with damage to the otolith organs. The aim of this study was to investigate whether aging is a risk factor for otolith organ dysfunction in idiopathic BPPV. We retrospectively reviewed the medical records of 112 consecutive idiopathic BPPV patients who underwent cervical VEMP testing to air-conducted sound (ACS cVEMP), ocular VEMP testing to bone-conducted vibration (BCV oVEMP), and caloric testing. We performed binomial logistic regression analyses to see whether age, the side affected by BPPV or the canal affected by BPPV have an association with the presence of peripheral vestibular dysfunction in idiopathic BPPV patients. The elderly group (aged ≥65 years) had a significantly positive association with abnormalities in BCV oVEMPs (p = 0.0109), while the side affected by BPPV (p = 0.598) and the canal affected by BPPV (p = 0.576) did not. The odds ratio of the abnormal BCV oVEMPs for the elderly group compared with the non-elderly group (aged < 65 years) was 2.676 (95% confidence interval, 1.254–5.079). The elderly group had no significant association with the abnormalities in ACS cVEMPs (p = 0.0955) or caloric testing (p = 0.488). Dysfunction of the utricle, where the dislodgement of the otoconia mainly occurs, is affected by aging in idiopathic BPPV. |
| first_indexed | 2024-12-22T10:12:20Z |
| format | Article |
| id | doaj.art-ed23a139ad614819b5c6ccde20f929be |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-22T10:12:20Z |
| publishDate | 2018-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-ed23a139ad614819b5c6ccde20f929be2022-12-21T18:29:50ZengFrontiers Media S.A.Frontiers in Neurology1664-22952018-12-01910.3389/fneur.2018.01049429162Aging Is a Risk Factor for Utricular Dysfunction in Idiopathic Benign Paroxysmal Positional VertigoChisato Fujimoto0Chisato Fujimoto1Takuya Kawahara2Makoto Kinoshita3Yayoi S. Kikkawa4Keiko Sugasawa5Masato Yagi6Tatsuya Yamasoba7Shinichi Iwasaki8Toshihisa Murofushi9Toshihisa Murofushi10Department of Otolaryngology, Tokyo Teishin Hospital, Tokyo, JapanDepartment of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, JapanBiostatistics Division, Clinical Research Support Center, The University of Tokyo Hospital, Tokyo, JapanDepartment of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Otolaryngology, Tokyo Teishin Hospital, Tokyo, JapanDepartment of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Otolaryngology, Tokyo Teishin Hospital, Tokyo, JapanDepartment of Otolaryngology, School of Medicine, Teikyo University Mizonokuchi Hospital, Kawasaki, JapanBenign paroxysmal positional vertigo (BPPV) is the most common cause of balance disorders in the elderly. Dislodgement of the otoconia in BPPV might have an association with damage to the otolith organs. The aim of this study was to investigate whether aging is a risk factor for otolith organ dysfunction in idiopathic BPPV. We retrospectively reviewed the medical records of 112 consecutive idiopathic BPPV patients who underwent cervical VEMP testing to air-conducted sound (ACS cVEMP), ocular VEMP testing to bone-conducted vibration (BCV oVEMP), and caloric testing. We performed binomial logistic regression analyses to see whether age, the side affected by BPPV or the canal affected by BPPV have an association with the presence of peripheral vestibular dysfunction in idiopathic BPPV patients. The elderly group (aged ≥65 years) had a significantly positive association with abnormalities in BCV oVEMPs (p = 0.0109), while the side affected by BPPV (p = 0.598) and the canal affected by BPPV (p = 0.576) did not. The odds ratio of the abnormal BCV oVEMPs for the elderly group compared with the non-elderly group (aged < 65 years) was 2.676 (95% confidence interval, 1.254–5.079). The elderly group had no significant association with the abnormalities in ACS cVEMPs (p = 0.0955) or caloric testing (p = 0.488). Dysfunction of the utricle, where the dislodgement of the otoconia mainly occurs, is affected by aging in idiopathic BPPV.https://www.frontiersin.org/article/10.3389/fneur.2018.01049/fullagingbenign paroxysmal positional vertigorisk factorsvestibular diseasesvestibular function tests |
| spellingShingle | Chisato Fujimoto Chisato Fujimoto Takuya Kawahara Makoto Kinoshita Yayoi S. Kikkawa Keiko Sugasawa Masato Yagi Tatsuya Yamasoba Shinichi Iwasaki Toshihisa Murofushi Toshihisa Murofushi Aging Is a Risk Factor for Utricular Dysfunction in Idiopathic Benign Paroxysmal Positional Vertigo Frontiers in Neurology aging benign paroxysmal positional vertigo risk factors vestibular diseases vestibular function tests |
| title | Aging Is a Risk Factor for Utricular Dysfunction in Idiopathic Benign Paroxysmal Positional Vertigo |
| title_full | Aging Is a Risk Factor for Utricular Dysfunction in Idiopathic Benign Paroxysmal Positional Vertigo |
| title_fullStr | Aging Is a Risk Factor for Utricular Dysfunction in Idiopathic Benign Paroxysmal Positional Vertigo |
| title_full_unstemmed | Aging Is a Risk Factor for Utricular Dysfunction in Idiopathic Benign Paroxysmal Positional Vertigo |
| title_short | Aging Is a Risk Factor for Utricular Dysfunction in Idiopathic Benign Paroxysmal Positional Vertigo |
| title_sort | aging is a risk factor for utricular dysfunction in idiopathic benign paroxysmal positional vertigo |
| topic | aging benign paroxysmal positional vertigo risk factors vestibular diseases vestibular function tests |
| url | https://www.frontiersin.org/article/10.3389/fneur.2018.01049/full |
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