The Relationship between Air Pollution and Brain Cancer: A Systematic Review and Meta-Analysis
Background: There is very little epidemiological evidence on the effects of ambient air pollution on brain tumor risk. The purpose of this study was to determine the relationship between exposure to air pollution and the incidence of brain tumors. Methods: A comprehensive literature search in five i...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Ubiquity Press
2023-06-01
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| Series: | Annals of Global Health |
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| Online Access: | https://account.annalsofglobalhealth.org/index.php/up-j-agh/article/view/3889 |
| _version_ | 1797777895373930496 |
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| author | Soheil Hassanipour Hossein-Ali Nikbakht Abdeltif Amrane Morteza Arab-Zozani Layla Shojaie Saeid Rostami Ahmad Badeenezhad |
| author_facet | Soheil Hassanipour Hossein-Ali Nikbakht Abdeltif Amrane Morteza Arab-Zozani Layla Shojaie Saeid Rostami Ahmad Badeenezhad |
| author_sort | Soheil Hassanipour |
| collection | DOAJ |
| description | Background: There is very little epidemiological evidence on the effects of ambient air pollution on brain tumor risk. The purpose of this study was to determine the relationship between exposure to air pollution and the incidence of brain tumors. Methods: A comprehensive literature search in five international databases, including PubMed/Medline, ProQuest, Scopus, Embase, and ISI/WOS on April 15, 2019, was conducted. The methodology of the present study was based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) statement. The Newcastle-Ottawa Quality Assessment Form was used to evaluate the quality of the selected papers. Results: Five studies that measured adult brain tumors as well as their long-term exposure to at least one of the pollutants criteria for air pollution, PM2.5 absorbance, and proximity to traffic (Trafnear) were reviewed. The results showed that the pooled relative risk (RR) for incidence of brain tumor and long term exposure to Trafnear, PM2.5, PM2.5 absorbance, O3 and NOx were RR = 1.07, (95% CI 0.99–1.16), P = 0.079, for Trafnear; RR = 0.90, (95% CI 0.80–1.00), P = 0.064 for PM2.5; RR = 1.63, (95% CI 1.04–2.55), P = 0.031 for PM2.5 absorbance; RR = 1.3, (95% CI 1.03–1.6), P = 0.023 for O3; and RR = 1.16, (95% CI 0.93–1.45), P = 0.173 for NOx. Exposure to other air pollutants had no statistically significant association with brain tumor incidence. Conclusion: The results showed that exposure to air pollutants, such as O3 and PM2.5 absorbance, had the highest correlation with brain tumor incidence. They also showed an absence of correlation between exposure to certain pollutants (SO2, CO, NO2, PM10, PM2.5) and brain tumor incidence. |
| first_indexed | 2024-03-12T23:10:06Z |
| format | Article |
| id | doaj.art-ed25758ba5dc4cfd95b6d58046c7b706 |
| institution | Directory Open Access Journal |
| issn | 2214-9996 |
| language | English |
| last_indexed | 2024-03-12T23:10:06Z |
| publishDate | 2023-06-01 |
| publisher | Ubiquity Press |
| record_format | Article |
| series | Annals of Global Health |
| spelling | doaj.art-ed25758ba5dc4cfd95b6d58046c7b7062023-07-18T07:49:52ZengUbiquity PressAnnals of Global Health2214-99962023-06-01891454510.5334/aogh.38893811The Relationship between Air Pollution and Brain Cancer: A Systematic Review and Meta-AnalysisSoheil Hassanipour0https://orcid.org/0000-0002-6661-4908Hossein-Ali Nikbakht1https://orcid.org/0000-0002-8556-431XAbdeltif Amrane2https://orcid.org/0000-0003-2622-2384Morteza Arab-Zozani3https://orcid.org/0000-0001-7223-6707Layla Shojaie4https://orcid.org/0000-0002-5020-5181Saeid Rostami5https://orcid.org/0000-0002-6455-4681Ahmad Badeenezhad6https://orcid.org/0000-0003-4830-9691Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, RashtSocial Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, BabolUniv Rennes, Ecole Nationale Supérieure de Chimie de Rennes, CNRS, ISCR-UMR 6226, F-35000 RennesSocial Determinants of Health Research Center, Birjand University of Medical Sciences, BirjandDivision of GI/Liver, Department of Medicine, Keck school of Medicine, University of Southern California, Los Angeles, CADepartment of Environmental Health Engineering, Shiraz University of Medical Science, ShirazDepartment of Environmental Health Engineering, School of Medical Sciences, Behbahan Faculty of Medical Sciences, BehbahanBackground: There is very little epidemiological evidence on the effects of ambient air pollution on brain tumor risk. The purpose of this study was to determine the relationship between exposure to air pollution and the incidence of brain tumors. Methods: A comprehensive literature search in five international databases, including PubMed/Medline, ProQuest, Scopus, Embase, and ISI/WOS on April 15, 2019, was conducted. The methodology of the present study was based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) statement. The Newcastle-Ottawa Quality Assessment Form was used to evaluate the quality of the selected papers. Results: Five studies that measured adult brain tumors as well as their long-term exposure to at least one of the pollutants criteria for air pollution, PM2.5 absorbance, and proximity to traffic (Trafnear) were reviewed. The results showed that the pooled relative risk (RR) for incidence of brain tumor and long term exposure to Trafnear, PM2.5, PM2.5 absorbance, O3 and NOx were RR = 1.07, (95% CI 0.99–1.16), P = 0.079, for Trafnear; RR = 0.90, (95% CI 0.80–1.00), P = 0.064 for PM2.5; RR = 1.63, (95% CI 1.04–2.55), P = 0.031 for PM2.5 absorbance; RR = 1.3, (95% CI 1.03–1.6), P = 0.023 for O3; and RR = 1.16, (95% CI 0.93–1.45), P = 0.173 for NOx. Exposure to other air pollutants had no statistically significant association with brain tumor incidence. Conclusion: The results showed that exposure to air pollutants, such as O3 and PM2.5 absorbance, had the highest correlation with brain tumor incidence. They also showed an absence of correlation between exposure to certain pollutants (SO2, CO, NO2, PM10, PM2.5) and brain tumor incidence.https://account.annalsofglobalhealth.org/index.php/up-j-agh/article/view/3889brain cancerair pollutionsystematic reviewmeta-analysis |
| spellingShingle | Soheil Hassanipour Hossein-Ali Nikbakht Abdeltif Amrane Morteza Arab-Zozani Layla Shojaie Saeid Rostami Ahmad Badeenezhad The Relationship between Air Pollution and Brain Cancer: A Systematic Review and Meta-Analysis Annals of Global Health brain cancer air pollution systematic review meta-analysis |
| title | The Relationship between Air Pollution and Brain Cancer: A Systematic Review and Meta-Analysis |
| title_full | The Relationship between Air Pollution and Brain Cancer: A Systematic Review and Meta-Analysis |
| title_fullStr | The Relationship between Air Pollution and Brain Cancer: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | The Relationship between Air Pollution and Brain Cancer: A Systematic Review and Meta-Analysis |
| title_short | The Relationship between Air Pollution and Brain Cancer: A Systematic Review and Meta-Analysis |
| title_sort | relationship between air pollution and brain cancer a systematic review and meta analysis |
| topic | brain cancer air pollution systematic review meta-analysis |
| url | https://account.annalsofglobalhealth.org/index.php/up-j-agh/article/view/3889 |
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