The soluble mannose receptor (sMR/sCD206) in critically ill patients with invasive fungal infections, bacterial infections or non-infectious inflammation: a secondary analysis of the EPaNIC RCT

The soluble mannose receptor (sMR/sCD206) in critically ill patients with invasive fungal infections, bacterial infections or non-infectious inflammation: a secondary analysis of the EPaNIC RCT

Abstract Background Invasive fungal infections (IFI) are difficult to diagnose, especially in critically ill patients. As the mannose receptor (MR) is shed from macrophage cell surfaces after exposure to fungi, we investigate whether its soluble serum form (sMR) can serve as a biomarker of IFI. Meth...

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Bibliographic Details
Main Authors: Greet De Vlieger, Ilse Vanhorebeek, Pieter J. Wouters, Inge Derese, Michael P. Casaer, Yves Debaveye, Greet Hermans, Philippe Meersseman, Holger J. Møller, Greet Van den Berghe, Catherine Ingels
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Critical Care
Subjects:
Invasive fungal infection
Inflammation
Soluble mannose receptor
sMR
Soluble CD206
sCD206
Online Access:http://link.springer.com/article/10.1186/s13054-019-2549-8

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