Antimicrobial Efficacy of Silver Nanoparticles against Candida Albicans
Current treatment protocols for patients diagnosed with denture stomatitis are under scrutiny, and alternative options are being explored by researchers. The aim of this systematic review was to determine if silver nanoparticles inhibit the growth of <i>Candida albicans</i>, and the rese...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/15/16/5666 |
| _version_ | 1797443760194322432 |
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| author | Razia Z. Adam Saadika B. Khan |
| author_facet | Razia Z. Adam Saadika B. Khan |
| author_sort | Razia Z. Adam |
| collection | DOAJ |
| description | Current treatment protocols for patients diagnosed with denture stomatitis are under scrutiny, and alternative options are being explored by researchers. The aim of this systematic review was to determine if silver nanoparticles inhibit the growth of <i>Candida albicans</i>, and the research question addressed was: <i>In adults, do silver nanoparticles inhibit the growth of Candida albicans in acrylic dentures and denture liners compared to normal treatment options</i>. A systematic review was the chosen methodology, and criteria were formulated to include all types of studies, including clinical and laboratory designs where the aim was tested. Of the 18 included studies, only one was a clinical trial, and 17 were in vitro research. The inhibition of candidal growth was based on the % concentration of AgNPs included within the denture acrylic and denture liner. As the % AgNPs increased, candida growth was reduced. This was reported as a reduction of candidal colony forming units in the studies. The quality of the included studies was mostly acceptable, as seen from the structured and validated assessments completed. |
| first_indexed | 2024-03-09T13:02:16Z |
| format | Article |
| id | doaj.art-ed284cb1e35d42c8b05f07028d8ea9ef |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-09T13:02:16Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-ed284cb1e35d42c8b05f07028d8ea9ef2023-11-30T21:53:20ZengMDPI AGMaterials1996-19442022-08-011516566610.3390/ma15165666Antimicrobial Efficacy of Silver Nanoparticles against Candida AlbicansRazia Z. Adam0Saadika B. Khan1Department of Restorative Dentistry, Faculty of Dentistry, University of the Western Cape, Cape Town 7535, South AfricaDepartment of Restorative Dentistry, Faculty of Dentistry, University of the Western Cape, Cape Town 7535, South AfricaCurrent treatment protocols for patients diagnosed with denture stomatitis are under scrutiny, and alternative options are being explored by researchers. The aim of this systematic review was to determine if silver nanoparticles inhibit the growth of <i>Candida albicans</i>, and the research question addressed was: <i>In adults, do silver nanoparticles inhibit the growth of Candida albicans in acrylic dentures and denture liners compared to normal treatment options</i>. A systematic review was the chosen methodology, and criteria were formulated to include all types of studies, including clinical and laboratory designs where the aim was tested. Of the 18 included studies, only one was a clinical trial, and 17 were in vitro research. The inhibition of candidal growth was based on the % concentration of AgNPs included within the denture acrylic and denture liner. As the % AgNPs increased, candida growth was reduced. This was reported as a reduction of candidal colony forming units in the studies. The quality of the included studies was mostly acceptable, as seen from the structured and validated assessments completed.https://www.mdpi.com/1996-1944/15/16/5666denture stomatitis<i>Candida albicans</i>dentures and denture linerssilver nanoparticlescolony forming units |
| spellingShingle | Razia Z. Adam Saadika B. Khan Antimicrobial Efficacy of Silver Nanoparticles against Candida Albicans Materials denture stomatitis <i>Candida albicans</i> dentures and denture liners silver nanoparticles colony forming units |
| title | Antimicrobial Efficacy of Silver Nanoparticles against Candida Albicans |
| title_full | Antimicrobial Efficacy of Silver Nanoparticles against Candida Albicans |
| title_fullStr | Antimicrobial Efficacy of Silver Nanoparticles against Candida Albicans |
| title_full_unstemmed | Antimicrobial Efficacy of Silver Nanoparticles against Candida Albicans |
| title_short | Antimicrobial Efficacy of Silver Nanoparticles against Candida Albicans |
| title_sort | antimicrobial efficacy of silver nanoparticles against candida albicans |
| topic | denture stomatitis <i>Candida albicans</i> dentures and denture liners silver nanoparticles colony forming units |
| url | https://www.mdpi.com/1996-1944/15/16/5666 |
| work_keys_str_mv | AT raziazadam antimicrobialefficacyofsilvernanoparticlesagainstcandidaalbicans AT saadikabkhan antimicrobialefficacyofsilvernanoparticlesagainstcandidaalbicans |