18α-Glycyrrhetinic Acid Induces Apoptosis of HL-60 Human Leukemia Cells through Caspases- and Mitochondria-Dependent Signaling Pathways
In this study we investigate the molecular mechanisms of caspases and mitochondria in the extrinsic and intrinsic signal apoptosis pathways in human leukemia HL-60 cells after in vitro exposure to 18α-glycyrrhetinic acid (18α-GA). Cells were exposed to 18α-GA at various concentrations for various ti...
Main Authors: | Yi-Chang Huang, Chao-Lin Kuo, Kung-Wen Lu, Jen-Jyh Lin, Jiun-Long Yang, Rick Sai-Chuen Wu, Ping-Ping Wu, Jing-Gung Chung |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-07-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/21/7/872 |
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