Hemolysis, Elevated Liver Enzymes, Low Platelets Syndrome Superimposed on Hemolytic Uremic Syndrome
Abstract A pregnancy complicated by typical hemolytic uremic syndrome (HUS) and hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome is reported. At 20 weeks of gestation, a case of HUS was diagnosed, with Shiga toxin-producing Escherichia coli identified. Plasmapheresis allowed continu...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
2017-04-01
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| Series: | Revista Brasileira de Ginecologia e Obstetrícia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032017000400195&tlng=en |
| _version_ | 1818974955372544000 |
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| author | Inês Martins Madalena Gomes Conceição Paulo Pereira Gomes Nuno Clode |
| author_facet | Inês Martins Madalena Gomes Conceição Paulo Pereira Gomes Nuno Clode |
| author_sort | Inês Martins |
| collection | DOAJ |
| description | Abstract A pregnancy complicated by typical hemolytic uremic syndrome (HUS) and hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome is reported. At 20 weeks of gestation, a case of HUS was diagnosed, with Shiga toxin-producing Escherichia coli identified. Plasmapheresis allowed continuation of the pregnancy for 5 weeks. Superimposed preeclampsia and HELLP syndrome were diagnosed after the establishment of nephrotic range proteinuria, hypertension and recurrence of hemolysis. This is a singular case, as it demonstrates that HELLP syndrome can superimpose upon HUS, a fact that can impact future research on reproductive immunology. It also reminds clinicians that the overlapping of clinical and laboratory findings in HELLP syndrome makes the diagnosis of other thrombotic microangiopathies during pregnancy a clinical challenge. |
| first_indexed | 2024-12-20T15:48:17Z |
| format | Article |
| id | doaj.art-ed2af0b5fbc747378270cc6be62ce25a |
| institution | Directory Open Access Journal |
| issn | 0100-7203 |
| language | English |
| last_indexed | 2024-12-20T15:48:17Z |
| publishDate | 2017-04-01 |
| publisher | Federação Brasileira das Sociedades de Ginecologia e Obstetrícia |
| record_format | Article |
| series | Revista Brasileira de Ginecologia e Obstetrícia |
| spelling | doaj.art-ed2af0b5fbc747378270cc6be62ce25a2022-12-21T19:34:50ZengFederação Brasileira das Sociedades de Ginecologia e ObstetríciaRevista Brasileira de Ginecologia e Obstetrícia0100-72032017-04-0139419519810.1055/s-0037-1600124Hemolysis, Elevated Liver Enzymes, Low Platelets Syndrome Superimposed on Hemolytic Uremic SyndromeInês MartinsMadalena Gomes ConceiçãoPaulo Pereira GomesNuno ClodeAbstract A pregnancy complicated by typical hemolytic uremic syndrome (HUS) and hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome is reported. At 20 weeks of gestation, a case of HUS was diagnosed, with Shiga toxin-producing Escherichia coli identified. Plasmapheresis allowed continuation of the pregnancy for 5 weeks. Superimposed preeclampsia and HELLP syndrome were diagnosed after the establishment of nephrotic range proteinuria, hypertension and recurrence of hemolysis. This is a singular case, as it demonstrates that HELLP syndrome can superimpose upon HUS, a fact that can impact future research on reproductive immunology. It also reminds clinicians that the overlapping of clinical and laboratory findings in HELLP syndrome makes the diagnosis of other thrombotic microangiopathies during pregnancy a clinical challenge.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032017000400195&tlng=enHELLP syndromehemolytic uremic syndromethrombotic microangiopathies |
| spellingShingle | Inês Martins Madalena Gomes Conceição Paulo Pereira Gomes Nuno Clode Hemolysis, Elevated Liver Enzymes, Low Platelets Syndrome Superimposed on Hemolytic Uremic Syndrome Revista Brasileira de Ginecologia e Obstetrícia HELLP syndrome hemolytic uremic syndrome thrombotic microangiopathies |
| title | Hemolysis, Elevated Liver Enzymes, Low Platelets Syndrome Superimposed on Hemolytic Uremic Syndrome |
| title_full | Hemolysis, Elevated Liver Enzymes, Low Platelets Syndrome Superimposed on Hemolytic Uremic Syndrome |
| title_fullStr | Hemolysis, Elevated Liver Enzymes, Low Platelets Syndrome Superimposed on Hemolytic Uremic Syndrome |
| title_full_unstemmed | Hemolysis, Elevated Liver Enzymes, Low Platelets Syndrome Superimposed on Hemolytic Uremic Syndrome |
| title_short | Hemolysis, Elevated Liver Enzymes, Low Platelets Syndrome Superimposed on Hemolytic Uremic Syndrome |
| title_sort | hemolysis elevated liver enzymes low platelets syndrome superimposed on hemolytic uremic syndrome |
| topic | HELLP syndrome hemolytic uremic syndrome thrombotic microangiopathies |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032017000400195&tlng=en |
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