Alternative methods to analyse the impact of HIV mutations on virological response to antiviral therapy

Alternative methods to analyse the impact of HIV mutations on virological response to antiviral therapy

<p>Abstract</p> <p>Background</p> <p>Principal component analysis (PCA) and partial least square (PLS) regression may be useful to summarize the HIV genotypic information. Without pre-selection each mutation presented in at least one patient is considered with a differe...

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Main Authors: Neau Didier, Breilh Dominique, Pellegrin Isabelle, Commenges Daniel, Wittkop Linda, Lacoste Denis, Pellegrin Jean-Luc, Chêne Geneviève, Dabis François, Thiébaut Rodolphe
Format: Article
Language:English
Published: BMC 2008-10-01
Series:BMC Medical Research Methodology
Online Access:http://www.biomedcentral.com/1471-2288/8/68

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