PSMB1 Negatively Regulates the Innate Antiviral Immunity by Facilitating Degradation of IKK-ε

PSMB1 Negatively Regulates the Innate Antiviral Immunity by Facilitating Degradation of IKK-ε

Proteasome is a large protein complex, which degrades most intracellular proteins. It regulates numerous cellular processes, including the removal of misfolded or unfolded proteins, cell cycle control, and regulation of apoptosis. However, the function of proteasome subunits in viral immunity has no...

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Bibliographic Details
Main Authors: Fangyi Wu, Zhenmin Niu, Bin Zhou, Pengcheng Li, Feng Qian
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Viruses
Subjects:
PSMB1
IKK-ε
innate immunity
cytokine
RIG-I
TLR3
Online Access:https://www.mdpi.com/1999-4915/11/2/99

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