TNFα is a key trigger of inflammation in diet-induced non-obese MASLD in mice

TNFα is a key trigger of inflammation in diet-induced non-obese MASLD in mice

Tumor necrosis factor alpha (TNFα) is thought to be a critical factor in the development of metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we determined the effects of a treatment with the anti-TNFα antibody infliximab and a genetic deletion of TNFα, respectively, in the dev...

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Bibliographic Details
Main Authors: Katharina Burger, Finn Jung, Anja Baumann, Annette Brandt, Raphaela Staltner, Victor Sánchez, Ina Bergheim
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Redox Biology
Subjects:
Fatty liver
MASH
Endotoxin
Insulin resistance
Intestinal barrier
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723002719

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