Influenza A virus modulates ACE2 expression and SARS-CoV-2 infectivity in human cardiomyocytes

Influenza A virus modulates ACE2 expression and SARS-CoV-2 infectivity in human cardiomyocytes

Summary: Influenza A virus (IAV) and SARS-CoV-2 virus are both acute respiratory viruses currently circulating in the human population. This study aims to determine the impact of IAV infection on SARS-CoV-2 pathogenesis and cardiomyocyte function. Infection of human bronchial epithelial cells (HBEC)...

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Bibliographic Details
Main Authors: Qian Wu, Naresh Kumar, William P. Lafuse, Omar Santiagonunez Ahumada, Noushin Saljoughian, Elizabeth Whetstone, Ashley Zani, Ashley K. Patton, Mona El Refaey, Amy Webb, Maciej Pietrzak, Lianbo Yu, Mahesh KC, Mark E. Peeples, Latha P. Ganesan, Jacob S. Yount, Murugesan V.S. Rajaram
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:iScience
Subjects:
Protein
Virology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222019745

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