Self-sampling is appropriate for detection of <it>Staphylococcus aureus</it>: a validation study
<p>Abstract</p> <p>Background</p> <p>Studies frequently use nasal swabs to determine <it>Staphylococcus aureus</it> carriage. Self-sampling would be extremely useful in an outhospital research situation, but has not been studied in a healthy population. We s...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2012-11-01
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| Series: | Antimicrobial Resistance and Infection Control |
| Subjects: | |
| Online Access: | http://www.aricjournal.com/content/1/1/34 |
| _version_ | 1811277783835344896 |
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| author | van Cleef Brigitte AGL van Rijen Miranda Ferket Marianne Kluytmans Jan AJW |
| author_facet | van Cleef Brigitte AGL van Rijen Miranda Ferket Marianne Kluytmans Jan AJW |
| author_sort | van Cleef Brigitte AGL |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Studies frequently use nasal swabs to determine <it>Staphylococcus aureus</it> carriage. Self-sampling would be extremely useful in an outhospital research situation, but has not been studied in a healthy population. We studied the similarity of self-samples and investigator-samples in nares and pharynxes of healthy study subjects (hospital staff) in the Netherlands.</p> <p>Methods</p> <p>One hundred and five nursing personnel members were sampled 4 times in random order after viewing an instruction paper: 1) nasal self-sample, 2) pharyngeal self-sample, 3) nasal investigator-sample, and 4) pharyngeal investigator-sample.</p> <p>Results</p> <p>For nasal samples, agreement is 93% with a kappa coefficient of 0.85 (95% CI 0.74-0.96), indicating excellent agreement, for pharyngeal samples agreement is 83% and the kappa coefficient is 0.60 (95% CI 0.43-0.76), indicating good agreement. In both sampling sites self-samples even detected more <it>S. aureus</it> than investigator-samples.</p> <p>Conclusions</p> <p>This means that self-samples are appropriate for detection of <it>Staphylococcus aureus</it> and methicillin-resistant <it>Staphylococcus aureus</it>.</p> |
| first_indexed | 2024-04-13T00:22:24Z |
| format | Article |
| id | doaj.art-ed3705d1ab6345cd8d1bad20b4be6d44 |
| institution | Directory Open Access Journal |
| issn | 2047-2994 |
| language | English |
| last_indexed | 2024-04-13T00:22:24Z |
| publishDate | 2012-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Antimicrobial Resistance and Infection Control |
| spelling | doaj.art-ed3705d1ab6345cd8d1bad20b4be6d442022-12-22T03:10:43ZengBMCAntimicrobial Resistance and Infection Control2047-29942012-11-01113410.1186/2047-2994-1-34Self-sampling is appropriate for detection of <it>Staphylococcus aureus</it>: a validation studyvan Cleef Brigitte AGLvan Rijen MirandaFerket MarianneKluytmans Jan AJW<p>Abstract</p> <p>Background</p> <p>Studies frequently use nasal swabs to determine <it>Staphylococcus aureus</it> carriage. Self-sampling would be extremely useful in an outhospital research situation, but has not been studied in a healthy population. We studied the similarity of self-samples and investigator-samples in nares and pharynxes of healthy study subjects (hospital staff) in the Netherlands.</p> <p>Methods</p> <p>One hundred and five nursing personnel members were sampled 4 times in random order after viewing an instruction paper: 1) nasal self-sample, 2) pharyngeal self-sample, 3) nasal investigator-sample, and 4) pharyngeal investigator-sample.</p> <p>Results</p> <p>For nasal samples, agreement is 93% with a kappa coefficient of 0.85 (95% CI 0.74-0.96), indicating excellent agreement, for pharyngeal samples agreement is 83% and the kappa coefficient is 0.60 (95% CI 0.43-0.76), indicating good agreement. In both sampling sites self-samples even detected more <it>S. aureus</it> than investigator-samples.</p> <p>Conclusions</p> <p>This means that self-samples are appropriate for detection of <it>Staphylococcus aureus</it> and methicillin-resistant <it>Staphylococcus aureus</it>.</p>http://www.aricjournal.com/content/1/1/34Self-sampling<it>Staphylcococcus aureus</it>MRSAValidation |
| spellingShingle | van Cleef Brigitte AGL van Rijen Miranda Ferket Marianne Kluytmans Jan AJW Self-sampling is appropriate for detection of <it>Staphylococcus aureus</it>: a validation study Antimicrobial Resistance and Infection Control Self-sampling <it>Staphylcococcus aureus</it> MRSA Validation |
| title | Self-sampling is appropriate for detection of <it>Staphylococcus aureus</it>: a validation study |
| title_full | Self-sampling is appropriate for detection of <it>Staphylococcus aureus</it>: a validation study |
| title_fullStr | Self-sampling is appropriate for detection of <it>Staphylococcus aureus</it>: a validation study |
| title_full_unstemmed | Self-sampling is appropriate for detection of <it>Staphylococcus aureus</it>: a validation study |
| title_short | Self-sampling is appropriate for detection of <it>Staphylococcus aureus</it>: a validation study |
| title_sort | self sampling is appropriate for detection of it staphylococcus aureus it a validation study |
| topic | Self-sampling <it>Staphylcococcus aureus</it> MRSA Validation |
| url | http://www.aricjournal.com/content/1/1/34 |
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