Structural basis of dimerization of chemokine receptors CCR5 and CXCR4
Abstract G protein-coupled receptors (GPCRs) are prominent drug targets responsible for extracellular-to-intracellular signal transduction. GPCRs can form functional dimers that have been poorly characterized so far. Here, we show the dimerization mechanism of the chemokine receptors CCR5 and CXCR4...
Main Authors: | Daniele Di Marino, Paolo Conflitti, Stefano Motta, Vittorio Limongelli |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-42082-z |
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