Quantification of Berberine in <i>Berberis vulgaris</i> L. Root Extract and Its Curative and Prophylactic Role in Cisplatin-Induced In Vivo Toxicity and In Vitro Cytotoxicity

Quantification of Berberine in <i>Berberis vulgaris</i> L. Root Extract and Its Curative and Prophylactic Role in Cisplatin-Induced In Vivo Toxicity and In Vitro Cytotoxicity

Cisplatin is amongst the most potent chemotherapeutic drugs with applications in more than 50% of cancer treatments, but dose-dependent side effects limit its usefulness. <i>Berberis vulgaris</i> L. (<i>B. vulgaris</i>) has a proven role in several therapeutic applications in...

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Bibliographic Details
Main Authors: Sarfraz Ahmad, Amina Hussain, Aroosha Hussain, Iskandar Abdullah, Muhammad Sajjad Ali, Matheus Froeyen, Muhammad Usman Mirza
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Antioxidants
Subjects:
cisplatin
<i>Berberis vulgaris</i>
high-performance liquid chromatography
nephrotoxicity
hepatotoxicity
hyperlipidemia
Online Access:https://www.mdpi.com/2076-3921/8/6/185

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