Opening up new fronts in the fight against cholesterol
An unexpected connection between a secretory protein called PCSK9 and Sec24A, a well known protein-transport protein, could lead to the development of novel treatments for patients with high levels of low-density lipoproteins in their blood.
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2013-04-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/00663 |
| _version_ | 1811180507183972352 |
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| author | Russell A DeBose-Boyd Jay D Horton |
| author_facet | Russell A DeBose-Boyd Jay D Horton |
| author_sort | Russell A DeBose-Boyd |
| collection | DOAJ |
| description | An unexpected connection between a secretory protein called PCSK9 and Sec24A, a well known protein-transport protein, could lead to the development of novel treatments for patients with high levels of low-density lipoproteins in their blood. |
| first_indexed | 2024-04-11T09:04:27Z |
| format | Article |
| id | doaj.art-ed40225913394f9ca6af695957257eec |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-11T09:04:27Z |
| publishDate | 2013-04-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-ed40225913394f9ca6af695957257eec2022-12-22T04:32:42ZengeLife Sciences Publications LtdeLife2050-084X2013-04-01210.7554/eLife.00663Opening up new fronts in the fight against cholesterolRussell A DeBose-Boyd0Jay D Horton1Department of Molecular Genetics and the Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, United StatesDepartments of Internal Medicine and Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, United StatesAn unexpected connection between a secretory protein called PCSK9 and Sec24A, a well known protein-transport protein, could lead to the development of novel treatments for patients with high levels of low-density lipoproteins in their blood.https://elifesciences.org/articles/00663Secretory pathwayCOP IICholesterol metabolism |
| spellingShingle | Russell A DeBose-Boyd Jay D Horton Opening up new fronts in the fight against cholesterol eLife Secretory pathway COP II Cholesterol metabolism |
| title | Opening up new fronts in the fight against cholesterol |
| title_full | Opening up new fronts in the fight against cholesterol |
| title_fullStr | Opening up new fronts in the fight against cholesterol |
| title_full_unstemmed | Opening up new fronts in the fight against cholesterol |
| title_short | Opening up new fronts in the fight against cholesterol |
| title_sort | opening up new fronts in the fight against cholesterol |
| topic | Secretory pathway COP II Cholesterol metabolism |
| url | https://elifesciences.org/articles/00663 |
| work_keys_str_mv | AT russelladeboseboyd openingupnewfrontsinthefightagainstcholesterol AT jaydhorton openingupnewfrontsinthefightagainstcholesterol |