A qualitative assessment of barriers and facilitators to antiretroviral adherence in Thai patients

Objectives: Excellent adherence to combination antiretroviral therapy can suppress HIV replication and produce life expectancies nearing those of individuals without HIV infection. This qualitative study sought to identify the barriers and facilitators to good antiretroviral medication adherence in...

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Main Authors: Melissa Phuphanich, Maneerat Rattanamahattana, Anchalee Avihingsanon, Ploenchan Chetchotisakd, Opass Putcharoen, Monica Gandhi, Annette H. Sohn, John Imrie, Praphan Phanuphak, Stephen J. Kerr
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Journal of Virus Eradication
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664020306920
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author Melissa Phuphanich
Maneerat Rattanamahattana
Anchalee Avihingsanon
Ploenchan Chetchotisakd
Opass Putcharoen
Monica Gandhi
Annette H. Sohn
John Imrie
Praphan Phanuphak
Stephen J. Kerr
author_facet Melissa Phuphanich
Maneerat Rattanamahattana
Anchalee Avihingsanon
Ploenchan Chetchotisakd
Opass Putcharoen
Monica Gandhi
Annette H. Sohn
John Imrie
Praphan Phanuphak
Stephen J. Kerr
author_sort Melissa Phuphanich
collection DOAJ
description Objectives: Excellent adherence to combination antiretroviral therapy can suppress HIV replication and produce life expectancies nearing those of individuals without HIV infection. This qualitative study sought to identify the barriers and facilitators to good antiretroviral medication adherence in Thai patients living with HIV. Methods: Semi-structured interviews were conducted with a convenience sample (n=21) of patients attending routine clinic visits at Srinagarind Hospital in Khon Kaen, or HIV-NAT, the Thai Red Cross AIDS Research Centre in Bangkok. Results: Median informant age was 43 years (range 27–60 years) and 43% were female. We identified key facilitators and barriers to adherence among HIV-infected Thai patients along three major themes (patient-related, health system-related and medication-related). Stigma was a primary concern for most informants, operating throughout Thai society to induce feelings of shame for Thai people living with HIV. Determination to stay healthy and incorporate taking cART into their daily routine were key components of good adherence. Supportive and trusting relationships, particularly with the clinic team, empowered patients to maintain good medication adherence. Conclusions: Changing public perceptions about HIV, and training of HIV clinic staff on the importance of trusting and supportive provider–patient relationships in promoting good health outcomes, will help Thailand achieve its aim of having zero new HIV infections, zero discrimination and zero AIDS-related deaths by 2030.
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spelling doaj.art-ed41472afdb94b6d8c383b4f74f6c7912022-12-21T22:33:43ZengElsevierJournal of Virus Eradication2055-66402016-01-01212227A qualitative assessment of barriers and facilitators to antiretroviral adherence in Thai patientsMelissa Phuphanich0Maneerat Rattanamahattana1Anchalee Avihingsanon2Ploenchan Chetchotisakd3Opass Putcharoen4Monica Gandhi5Annette H. Sohn6John Imrie7Praphan Phanuphak8Stephen J. Kerr9School of Medicine, University of California, San Francisco, USAFaculty of Pharmaceutical Sciences, Khon Kaen University, ThailandHIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand; Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandFaculty of Medicine, Khon Kaen University, ThailandFaculty of Medicine, Chulalongkorn University, Bangkok, ThailandSchool of Medicine, University of California, San Francisco, USATREAT Asia/amfAR –The Foundation for AIDS Research, Bangkok, ThailandCentre for Sexual Health and HIV Research, Department of Infection and Population Health, University College London, UK; Faculty of Arts and Social Sciences, University of New South Wales, Sydney, AustraliaHIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand; Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandHIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand; Kirby Institute, University of New South Wales, Sydney, Australia; Amsterdam Institute of Global Health and Development (AIGHD), the Netherlands; Corresponding author: Stephen J Kerr, HIV-NAT, Thai Red Cross AIDS Research Centre, 104 Ratchadamri Road, Bangkok, 10330, ThailandObjectives: Excellent adherence to combination antiretroviral therapy can suppress HIV replication and produce life expectancies nearing those of individuals without HIV infection. This qualitative study sought to identify the barriers and facilitators to good antiretroviral medication adherence in Thai patients living with HIV. Methods: Semi-structured interviews were conducted with a convenience sample (n=21) of patients attending routine clinic visits at Srinagarind Hospital in Khon Kaen, or HIV-NAT, the Thai Red Cross AIDS Research Centre in Bangkok. Results: Median informant age was 43 years (range 27–60 years) and 43% were female. We identified key facilitators and barriers to adherence among HIV-infected Thai patients along three major themes (patient-related, health system-related and medication-related). Stigma was a primary concern for most informants, operating throughout Thai society to induce feelings of shame for Thai people living with HIV. Determination to stay healthy and incorporate taking cART into their daily routine were key components of good adherence. Supportive and trusting relationships, particularly with the clinic team, empowered patients to maintain good medication adherence. Conclusions: Changing public perceptions about HIV, and training of HIV clinic staff on the importance of trusting and supportive provider–patient relationships in promoting good health outcomes, will help Thailand achieve its aim of having zero new HIV infections, zero discrimination and zero AIDS-related deaths by 2030.http://www.sciencedirect.com/science/article/pii/S2055664020306920adherence, HIV, Thailand, Southeast Asia, antiretroviral agents
spellingShingle Melissa Phuphanich
Maneerat Rattanamahattana
Anchalee Avihingsanon
Ploenchan Chetchotisakd
Opass Putcharoen
Monica Gandhi
Annette H. Sohn
John Imrie
Praphan Phanuphak
Stephen J. Kerr
A qualitative assessment of barriers and facilitators to antiretroviral adherence in Thai patients
Journal of Virus Eradication
adherence, HIV, Thailand, Southeast Asia, antiretroviral agents
title A qualitative assessment of barriers and facilitators to antiretroviral adherence in Thai patients
title_full A qualitative assessment of barriers and facilitators to antiretroviral adherence in Thai patients
title_fullStr A qualitative assessment of barriers and facilitators to antiretroviral adherence in Thai patients
title_full_unstemmed A qualitative assessment of barriers and facilitators to antiretroviral adherence in Thai patients
title_short A qualitative assessment of barriers and facilitators to antiretroviral adherence in Thai patients
title_sort qualitative assessment of barriers and facilitators to antiretroviral adherence in thai patients
topic adherence, HIV, Thailand, Southeast Asia, antiretroviral agents
url http://www.sciencedirect.com/science/article/pii/S2055664020306920
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