Antibiofilm activity of berberine and capsaicin in combination with quinolones against Staphylococcus aureus from bovine mastitis
Antimicrobial resistance which causes failure of antibiotic therapy has become a serious global issue nowadays. Bacteria develop resistance towards an antibacterial agent via many mechanisms. Biofilm formation by bacteria poses severe threat to the treatment of infections. The combination of plan...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Director of Academics and Research, Kerala Veterinary and Animal Sciences University
2022-06-01
|
| Series: | Journal of Veterinary and Animal Sciences |
| Subjects: | |
| Online Access: | https://jvas.in/public_html/upload/article_file/article_file_rf9e1p.pdf?t=rf9e1p |
| _version_ | 1811183636558381056 |
|---|---|
| author | Arya Mohan A. R. Nisha S. Sujith S. Suja Rani Naicy Thomas |
| author_facet | Arya Mohan A. R. Nisha S. Sujith S. Suja Rani Naicy Thomas |
| author_sort | Arya Mohan |
| collection | DOAJ |
| description | Antimicrobial resistance which causes failure of antibiotic therapy has become a serious global
issue nowadays. Bacteria develop resistance towards an antibacterial agent via many mechanisms.
Biofilm formation by bacteria poses severe threat to the treatment of infections. The combination of
plant molecules with antibiotics can combat antimicrobial resistance. In the present study, antibiofilm
activity of two plant molecules berberine and capsaicin was investigated against Staphylococcus
aureus isolates from bovine mastitis cases. Antibiotic sensitivity testing revealed that berberine
and capsaicin when combined with quinolones increased the diameter of zone of inhibition in
a dose dependent manner. In vitro biofilm assay using congo red agar plate method revealed
the antibiofilm activity of berberine and capsaicin in combination with quinolone antibiotics. The
study concludes that the combination of phytoconstituents with antibiotics can alleviate resistance
mechanisms in bacteria |
| first_indexed | 2024-04-11T09:50:15Z |
| format | Article |
| id | doaj.art-ed44808091d64fad9784d904d83252a7 |
| institution | Directory Open Access Journal |
| issn | 0971-0701 2582-0605 |
| language | English |
| last_indexed | 2024-04-11T09:50:15Z |
| publishDate | 2022-06-01 |
| publisher | Director of Academics and Research, Kerala Veterinary and Animal Sciences University |
| record_format | Article |
| series | Journal of Veterinary and Animal Sciences |
| spelling | doaj.art-ed44808091d64fad9784d904d83252a72022-12-22T04:30:51ZengDirector of Academics and Research, Kerala Veterinary and Animal Sciences UniversityJournal of Veterinary and Animal Sciences0971-07012582-06052022-06-0153225326110.51966/jvas.2022.53.2.253-261Antibiofilm activity of berberine and capsaicin in combination with quinolones against Staphylococcus aureus from bovine mastitisArya Mohan0https://orcid.org/0000-0003-2343-6213A. R. Nisha1S. Sujith2S. Suja Rani3Naicy Thomas4 MVSc Scholar, Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, IndiaAssistant Professor and Head, Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, IndiaAssistant Professor, Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, IndiaAssistant Professor, Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, IndiaAssistant Professor, Department of Animal Genetics and Breeding, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, IndiaAntimicrobial resistance which causes failure of antibiotic therapy has become a serious global issue nowadays. Bacteria develop resistance towards an antibacterial agent via many mechanisms. Biofilm formation by bacteria poses severe threat to the treatment of infections. The combination of plant molecules with antibiotics can combat antimicrobial resistance. In the present study, antibiofilm activity of two plant molecules berberine and capsaicin was investigated against Staphylococcus aureus isolates from bovine mastitis cases. Antibiotic sensitivity testing revealed that berberine and capsaicin when combined with quinolones increased the diameter of zone of inhibition in a dose dependent manner. In vitro biofilm assay using congo red agar plate method revealed the antibiofilm activity of berberine and capsaicin in combination with quinolone antibiotics. The study concludes that the combination of phytoconstituents with antibiotics can alleviate resistance mechanisms in bacteriahttps://jvas.in/public_html/upload/article_file/article_file_rf9e1p.pdf?t=rf9e1pantimicrobial resistancebiofilmstaphylococcus aureusbovine mastitis |
| spellingShingle | Arya Mohan A. R. Nisha S. Sujith S. Suja Rani Naicy Thomas Antibiofilm activity of berberine and capsaicin in combination with quinolones against Staphylococcus aureus from bovine mastitis Journal of Veterinary and Animal Sciences antimicrobial resistance biofilm staphylococcus aureus bovine mastitis |
| title | Antibiofilm activity of berberine and capsaicin in combination with quinolones against Staphylococcus aureus from bovine mastitis |
| title_full | Antibiofilm activity of berberine and capsaicin in combination with quinolones against Staphylococcus aureus from bovine mastitis |
| title_fullStr | Antibiofilm activity of berberine and capsaicin in combination with quinolones against Staphylococcus aureus from bovine mastitis |
| title_full_unstemmed | Antibiofilm activity of berberine and capsaicin in combination with quinolones against Staphylococcus aureus from bovine mastitis |
| title_short | Antibiofilm activity of berberine and capsaicin in combination with quinolones against Staphylococcus aureus from bovine mastitis |
| title_sort | antibiofilm activity of berberine and capsaicin in combination with quinolones against staphylococcus aureus from bovine mastitis |
| topic | antimicrobial resistance biofilm staphylococcus aureus bovine mastitis |
| url | https://jvas.in/public_html/upload/article_file/article_file_rf9e1p.pdf?t=rf9e1p |
| work_keys_str_mv | AT aryamohan antibiofilmactivityofberberineandcapsaicinincombinationwithquinolonesagainststaphylococcusaureusfrombovinemastitis AT arnisha antibiofilmactivityofberberineandcapsaicinincombinationwithquinolonesagainststaphylococcusaureusfrombovinemastitis AT ssujith antibiofilmactivityofberberineandcapsaicinincombinationwithquinolonesagainststaphylococcusaureusfrombovinemastitis AT ssujarani antibiofilmactivityofberberineandcapsaicinincombinationwithquinolonesagainststaphylococcusaureusfrombovinemastitis AT naicythomas antibiofilmactivityofberberineandcapsaicinincombinationwithquinolonesagainststaphylococcusaureusfrombovinemastitis |