Cancer-associated fibroblasts connect metastasis-promoting communication in colorectal cancer

Cancer-associated fibroblasts connect metastasis-promoting communication in colorectal cancer

Colorectal cancer progression and eventually metastasis is directed in many aspects by a circuitous ecosystem consisting of an extracellular matrix scaffold populated by cancer-associated fibroblasts (CAFs), endothelial cells and diverse immune cells. CAFs are recruited from local tissue-resident fi...

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Bibliographic Details
Main Authors:	Joke eTommelein, Laurine eVerset, Tom eBoterberg, Pieter eDemetter, Marc eBracke, Olivier eDe Wever
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-03-01
Series:	Frontiers in Oncology
Subjects:	colorectal cancer metastasis immune cells cancer-associated fibroblasts pericryptal fibroblasts
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00063/full

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