Mucosal Application of a Low-Energy Electron Inactivated Respiratory Syncytial Virus Vaccine Shows Protective Efficacy in an Animal Model

Mucosal Application of a Low-Energy Electron Inactivated Respiratory Syncytial Virus Vaccine Shows Protective Efficacy in an Animal Model

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections in the elderly and in children, associated with pediatric hospitalizations. Recently, first vaccines have been approved for people over 60 years of age applied by intramuscular injection. However, a vacc...

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Bibliographic Details
Main Authors: Valentina Eberlein, Mareike Ahrends, Lea Bayer, Julia Finkensieper, Joana Kira Besecke, Yaser Mansuroglu, Bastian Standfest, Franziska Lange, Simone Schopf, Martin Thoma, Jennifer Dressman, Christina Hesse, Sebastian Ulbert, Thomas Grunwald
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Viruses
Subjects:
respiratory syncytial virus
RSV
mucosal vaccine
inactivated vaccine
low-energy electron irradiation
LEEI
Online Access:https://www.mdpi.com/1999-4915/15/9/1846

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