Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus

Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus

It has been extensively reported that diabetes mellitus (DM) patients have a higher risk of developing Alzheimer's disease (AD), but a mechanistic connection between both pathologies has not been provided so far. Carbohydrate-derived advanced glycation endproducts (AGEs) have been implicated in...

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Bibliographic Details
Main Authors: Tony Valente, Alejandro Gella, Xavier Fernàndez-Busquets, Mercedes Unzeta, Nuria Durany
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Neurobiology of Disease
Subjects:
Abeta
Alzheimer's disease
RAGE
AGEs
Diabetes
Immunohistochemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109002496

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