Development of Methodology to Investigate the Surface SMALPome of Mammalian Cells

Development of Methodology to Investigate the Surface SMALPome of Mammalian Cells

Extraction of membrane proteins from biological membranes has traditionally involved detergents. In the past decade, a new technique has been developed, which uses styrene maleic acid (SMA) copolymers to extract membrane proteins into nanodiscs without the requirement of detergents. SMA nanodiscs ar...

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Bibliographic Details
Main Authors: Kerrie A. Morrison, Kate J. Heesom, Karen J. Edler, James Doutch, Gareth J. Price, Francoise Koumanov, Paul Whitley
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Molecular Biosciences
Subjects:
styrene maleic acid
SMA
mass spectrometry proteomics
SMALP
SMALPome
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.780033/full

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