Pharmacokinetics of tigecycline in critically ill patients with liver failure defined by maximal liver function capacity test (LiMAx)

Pharmacokinetics of tigecycline in critically ill patients with liver failure defined by maximal liver function capacity test (LiMAx)

Abstract Background In critically ill patients, tigecycline (TGC) remains an important therapeutic option due to its efficacy against multiresistant Gram-positive and Gram-negative bacteria. TGC is metabolized and eliminated predominantly by the liver. Critical illness-induced liver failure may have...

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Bibliographic Details
Main Authors: Rawan Alraish, Sebastian G. Wicha, Otto R. Frey, Anka C. Roehr, Johann Pratschke, Martin Stockmann, Tilo Wuensch, Magnus Kaffarnik
Format: Article
Language:English
Published: SpringerOpen 2020-08-01
Series:Annals of Intensive Care
Subjects:
Tigecycline
Liver function test
LiMAx
Pharmacokinetics
Online Access:http://link.springer.com/article/10.1186/s13613-020-00707-2

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