CLINICAL-EPIDEMIOLOGICAL RELATION BETWEEN SARS-COV-2 AND KAWASAKI DISEASE: AN INTEGRATIVE LITERATURE
ABSTRACT Objective: To analyze the current scientific literature to document, in an integrative review, the main findings that correlate Kawasaki disease (KD) to COVID-19. Data sources: The search was carried out in June 2020 in the following databases: Biblioteca Virtual em Saúde (BVS), periódi...
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| Format: | Article |
| Language: | English |
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Sociedade de Pediatria de São Paulo
2020-08-01
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| Series: | Revista Paulista de Pediatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822021000100503&tlng=pt |
| _version_ | 1818368087160782848 |
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| author | Bruna Silva dos Santos Fernanda Silva dos Santos Elaine Rossi Ribeiro |
| author_facet | Bruna Silva dos Santos Fernanda Silva dos Santos Elaine Rossi Ribeiro |
| author_sort | Bruna Silva dos Santos |
| collection | DOAJ |
| description | ABSTRACT Objective: To analyze the current scientific literature to document, in an integrative review, the main findings that correlate Kawasaki disease (KD) to COVID-19. Data sources: The search was carried out in June 2020 in the following databases: Biblioteca Virtual em Saúde (BVS), periódico da CAPES and U.S National Library of Medicine (PubMed). The combination of descriptors used was [(COVID-19 OR SARS-CoV-2) AND (Kawasaki disease)], and the inclusion criteria stipulated were studies published from January 2019 to June 2020, without restriction of language or location, and available online in full. News, editorials, comments, and letters, as well as duplicates and articles that did not answer the guiding question were excluded. Data synthesis: A total of 97 articles were identified, of which seven comprised this review. The association of KD to the new coronavirus appears to trigger a severe clinical condition of vasculitis. Different from the usual, in this inflammatory syndrome, patients are older, and prevalence is higher in children from African or Caribbean ancestry; clinical and laboratory manifestations are also atypical, with a predominance of abdominal complaints and exaggerated elevation of inflammatory markers. In addition, there was a greater report of rare complications and greater resistance to the recommended treatment for KD. Conclusions: Pediatric COVID-19 and its potential association to severe KD, still unfamiliar to health professionals, reinforces the importance of testing patients with vasculitis for the new coronavirus and the need to wage high surveillance and preparation of the health system during the current pandemic. |
| first_indexed | 2024-12-13T23:02:22Z |
| format | Article |
| id | doaj.art-ed6f4d3f37784233939a7daa768f79ad |
| institution | Directory Open Access Journal |
| issn | 1984-0462 |
| language | English |
| last_indexed | 2024-12-13T23:02:22Z |
| publishDate | 2020-08-01 |
| publisher | Sociedade de Pediatria de São Paulo |
| record_format | Article |
| series | Revista Paulista de Pediatria |
| spelling | doaj.art-ed6f4d3f37784233939a7daa768f79ad2022-12-21T23:28:22ZengSociedade de Pediatria de São PauloRevista Paulista de Pediatria1984-04622020-08-013910.1590/1984-0462/2021/39/2020217CLINICAL-EPIDEMIOLOGICAL RELATION BETWEEN SARS-COV-2 AND KAWASAKI DISEASE: AN INTEGRATIVE LITERATUREBruna Silva dos Santoshttps://orcid.org/0000-0002-9240-1877Fernanda Silva dos Santoshttps://orcid.org/0000-0003-3878-8457Elaine Rossi Ribeirohttps://orcid.org/0000-0003-3492-217XABSTRACT Objective: To analyze the current scientific literature to document, in an integrative review, the main findings that correlate Kawasaki disease (KD) to COVID-19. Data sources: The search was carried out in June 2020 in the following databases: Biblioteca Virtual em Saúde (BVS), periódico da CAPES and U.S National Library of Medicine (PubMed). The combination of descriptors used was [(COVID-19 OR SARS-CoV-2) AND (Kawasaki disease)], and the inclusion criteria stipulated were studies published from January 2019 to June 2020, without restriction of language or location, and available online in full. News, editorials, comments, and letters, as well as duplicates and articles that did not answer the guiding question were excluded. Data synthesis: A total of 97 articles were identified, of which seven comprised this review. The association of KD to the new coronavirus appears to trigger a severe clinical condition of vasculitis. Different from the usual, in this inflammatory syndrome, patients are older, and prevalence is higher in children from African or Caribbean ancestry; clinical and laboratory manifestations are also atypical, with a predominance of abdominal complaints and exaggerated elevation of inflammatory markers. In addition, there was a greater report of rare complications and greater resistance to the recommended treatment for KD. Conclusions: Pediatric COVID-19 and its potential association to severe KD, still unfamiliar to health professionals, reinforces the importance of testing patients with vasculitis for the new coronavirus and the need to wage high surveillance and preparation of the health system during the current pandemic.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822021000100503&tlng=ptMucocutaneous lymph node syndromeCoronavirus infectionsPandemicsBetacoronavirusInflammationChild |
| spellingShingle | Bruna Silva dos Santos Fernanda Silva dos Santos Elaine Rossi Ribeiro CLINICAL-EPIDEMIOLOGICAL RELATION BETWEEN SARS-COV-2 AND KAWASAKI DISEASE: AN INTEGRATIVE LITERATURE Revista Paulista de Pediatria Mucocutaneous lymph node syndrome Coronavirus infections Pandemics Betacoronavirus Inflammation Child |
| title | CLINICAL-EPIDEMIOLOGICAL RELATION BETWEEN SARS-COV-2 AND KAWASAKI DISEASE: AN INTEGRATIVE LITERATURE |
| title_full | CLINICAL-EPIDEMIOLOGICAL RELATION BETWEEN SARS-COV-2 AND KAWASAKI DISEASE: AN INTEGRATIVE LITERATURE |
| title_fullStr | CLINICAL-EPIDEMIOLOGICAL RELATION BETWEEN SARS-COV-2 AND KAWASAKI DISEASE: AN INTEGRATIVE LITERATURE |
| title_full_unstemmed | CLINICAL-EPIDEMIOLOGICAL RELATION BETWEEN SARS-COV-2 AND KAWASAKI DISEASE: AN INTEGRATIVE LITERATURE |
| title_short | CLINICAL-EPIDEMIOLOGICAL RELATION BETWEEN SARS-COV-2 AND KAWASAKI DISEASE: AN INTEGRATIVE LITERATURE |
| title_sort | clinical epidemiological relation between sars cov 2 and kawasaki disease an integrative literature |
| topic | Mucocutaneous lymph node syndrome Coronavirus infections Pandemics Betacoronavirus Inflammation Child |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822021000100503&tlng=pt |
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