The Effects of Alpha-Glycerylphosphorylcholine on Heart Rate Variability and Hemodynamic Variables Following Sprint Interval Exercise in Overweight and Obese Women
The current study examined the effects of Alpha-Glycerylphosphorylcholine (A-GPC) on heart rate variability (HRV) and hemodynamic responses following a sprint interval exercise (SIE) in women who were overweight or obese. Participants (<i>n</i> = 12, 31.0 ± 4.6 years; 29.4 ± 2.1 kg/m<...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-09-01
|
| Series: | Nutrients |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6643/14/19/3970 |
| _version_ | 1797477621588557824 |
|---|---|
| author | Seyedeh Parya Barzanjeh Linda S. Pescatello Arturo Figueroa Sajad Ahmadizad |
| author_facet | Seyedeh Parya Barzanjeh Linda S. Pescatello Arturo Figueroa Sajad Ahmadizad |
| author_sort | Seyedeh Parya Barzanjeh |
| collection | DOAJ |
| description | The current study examined the effects of Alpha-Glycerylphosphorylcholine (A-GPC) on heart rate variability (HRV) and hemodynamic responses following a sprint interval exercise (SIE) in women who were overweight or obese. Participants (<i>n</i> = 12, 31.0 ± 4.6 years; 29.4 ± 2.1 kg/m<sup>2</sup>) consumed 1000 mg of A-GPC or a placebo after eating breakfast in a randomized, double-blind cross-over design. After 60 min, participants performed two bouts of the SIE (30 s Wingate) interspersed with 4 min of active recovery (40 rpm). Hemodynamic variables and HRV domains were measured before and 60 min after the A-GPC consumption, immediately after SIE, and every 15 min up to 120 min during recovery. A-GPC consumption increased resting levels of both the time domain (Standard Deviation of RR wave intervals [SDNN] and percentage of interval differences of adjacent RR intervals greater than 50 ms [pNN50%]) and frequency domain (high frequency [HF] and low frequency [LF]) variables of HRV (<i>p</i> < 0.05). Moreover, HRV variables (except for LF/HF) decreased (<i>p</i> < 0.05) immediately after SIE in the A-GPC and placebo sessions. Systolic and diastolic blood pressure increased (<i>p</i> < 0.05) immediately after SIE in both trials. Both HRV and hemodynamic variables recovered (<i>p</i> < 0.05) faster in the A-GPC compared to the placebo session. We concluded that A-GPC consumption recovers HRV and blood pressure faster following strenuous exercise in overweight and obese women, and that it might favorably modify cardiac autonomic function. |
| first_indexed | 2024-03-09T21:20:19Z |
| format | Article |
| id | doaj.art-ed6f6729693e469997dcf149f760d44a |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T21:20:19Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-ed6f6729693e469997dcf149f760d44a2023-11-23T21:23:23ZengMDPI AGNutrients2072-66432022-09-011419397010.3390/nu14193970The Effects of Alpha-Glycerylphosphorylcholine on Heart Rate Variability and Hemodynamic Variables Following Sprint Interval Exercise in Overweight and Obese WomenSeyedeh Parya Barzanjeh0Linda S. Pescatello1Arturo Figueroa2Sajad Ahmadizad3Department of Biological Sciences in Sport, Faculty of Sports Sciences and Health, Shahid Beheshti University, Tehran 19839-69411, IranDepartment of Kinesiology, University of Connecticut, Storrs, CT 06269, USADepartment of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX 79409, USADepartment of Biological Sciences in Sport, Faculty of Sports Sciences and Health, Shahid Beheshti University, Tehran 19839-69411, IranThe current study examined the effects of Alpha-Glycerylphosphorylcholine (A-GPC) on heart rate variability (HRV) and hemodynamic responses following a sprint interval exercise (SIE) in women who were overweight or obese. Participants (<i>n</i> = 12, 31.0 ± 4.6 years; 29.4 ± 2.1 kg/m<sup>2</sup>) consumed 1000 mg of A-GPC or a placebo after eating breakfast in a randomized, double-blind cross-over design. After 60 min, participants performed two bouts of the SIE (30 s Wingate) interspersed with 4 min of active recovery (40 rpm). Hemodynamic variables and HRV domains were measured before and 60 min after the A-GPC consumption, immediately after SIE, and every 15 min up to 120 min during recovery. A-GPC consumption increased resting levels of both the time domain (Standard Deviation of RR wave intervals [SDNN] and percentage of interval differences of adjacent RR intervals greater than 50 ms [pNN50%]) and frequency domain (high frequency [HF] and low frequency [LF]) variables of HRV (<i>p</i> < 0.05). Moreover, HRV variables (except for LF/HF) decreased (<i>p</i> < 0.05) immediately after SIE in the A-GPC and placebo sessions. Systolic and diastolic blood pressure increased (<i>p</i> < 0.05) immediately after SIE in both trials. Both HRV and hemodynamic variables recovered (<i>p</i> < 0.05) faster in the A-GPC compared to the placebo session. We concluded that A-GPC consumption recovers HRV and blood pressure faster following strenuous exercise in overweight and obese women, and that it might favorably modify cardiac autonomic function.https://www.mdpi.com/2072-6643/14/19/3970autonomic systemcholineblood pressureexercise intensityWingate test |
| spellingShingle | Seyedeh Parya Barzanjeh Linda S. Pescatello Arturo Figueroa Sajad Ahmadizad The Effects of Alpha-Glycerylphosphorylcholine on Heart Rate Variability and Hemodynamic Variables Following Sprint Interval Exercise in Overweight and Obese Women Nutrients autonomic system choline blood pressure exercise intensity Wingate test |
| title | The Effects of Alpha-Glycerylphosphorylcholine on Heart Rate Variability and Hemodynamic Variables Following Sprint Interval Exercise in Overweight and Obese Women |
| title_full | The Effects of Alpha-Glycerylphosphorylcholine on Heart Rate Variability and Hemodynamic Variables Following Sprint Interval Exercise in Overweight and Obese Women |
| title_fullStr | The Effects of Alpha-Glycerylphosphorylcholine on Heart Rate Variability and Hemodynamic Variables Following Sprint Interval Exercise in Overweight and Obese Women |
| title_full_unstemmed | The Effects of Alpha-Glycerylphosphorylcholine on Heart Rate Variability and Hemodynamic Variables Following Sprint Interval Exercise in Overweight and Obese Women |
| title_short | The Effects of Alpha-Glycerylphosphorylcholine on Heart Rate Variability and Hemodynamic Variables Following Sprint Interval Exercise in Overweight and Obese Women |
| title_sort | effects of alpha glycerylphosphorylcholine on heart rate variability and hemodynamic variables following sprint interval exercise in overweight and obese women |
| topic | autonomic system choline blood pressure exercise intensity Wingate test |
| url | https://www.mdpi.com/2072-6643/14/19/3970 |
| work_keys_str_mv | AT seyedehparyabarzanjeh theeffectsofalphaglycerylphosphorylcholineonheartratevariabilityandhemodynamicvariablesfollowingsprintintervalexerciseinoverweightandobesewomen AT lindaspescatello theeffectsofalphaglycerylphosphorylcholineonheartratevariabilityandhemodynamicvariablesfollowingsprintintervalexerciseinoverweightandobesewomen AT arturofigueroa theeffectsofalphaglycerylphosphorylcholineonheartratevariabilityandhemodynamicvariablesfollowingsprintintervalexerciseinoverweightandobesewomen AT sajadahmadizad theeffectsofalphaglycerylphosphorylcholineonheartratevariabilityandhemodynamicvariablesfollowingsprintintervalexerciseinoverweightandobesewomen AT seyedehparyabarzanjeh effectsofalphaglycerylphosphorylcholineonheartratevariabilityandhemodynamicvariablesfollowingsprintintervalexerciseinoverweightandobesewomen AT lindaspescatello effectsofalphaglycerylphosphorylcholineonheartratevariabilityandhemodynamicvariablesfollowingsprintintervalexerciseinoverweightandobesewomen AT arturofigueroa effectsofalphaglycerylphosphorylcholineonheartratevariabilityandhemodynamicvariablesfollowingsprintintervalexerciseinoverweightandobesewomen AT sajadahmadizad effectsofalphaglycerylphosphorylcholineonheartratevariabilityandhemodynamicvariablesfollowingsprintintervalexerciseinoverweightandobesewomen |