Safety and long-term outcomes of remote cardiac rehabilitation in coronary heart disease patients: A systematic review

Objective To systematically review the safety and the long-term mortality and morbidity risk-rates of the remotely-delivered cardiac rehabilitation (RDCR) interventions in coronary heart disease (CHD) patients. Methods The protocol was registered in the International Prospective Register of Systemat...

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Main Authors: Varsamo Antoniou, Eleni Kapreli, Constantinos H Davos, Ladislav Batalik, Garyfallia Pepera
Format: Article
Language:English
Published: SAGE Publishing 2024-03-01
Series:Digital Health
Online Access:https://doi.org/10.1177/20552076241237661
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author Varsamo Antoniou
Eleni Kapreli
Constantinos H Davos
Ladislav Batalik
Garyfallia Pepera
author_facet Varsamo Antoniou
Eleni Kapreli
Constantinos H Davos
Ladislav Batalik
Garyfallia Pepera
author_sort Varsamo Antoniou
collection DOAJ
description Objective To systematically review the safety and the long-term mortality and morbidity risk-rates of the remotely-delivered cardiac rehabilitation (RDCR) interventions in coronary heart disease (CHD) patients. Methods The protocol was registered in the International Prospective Register of Systematic Reviews (CRD42023455471). Five databases (Pubmed, Scopus, Cochrane Central Register of Controlled Trials in the Cochrane Library, Cinahl and Web of Science) were reviewed from January 2012 up to August 2023. Inclusion criteria were: (a) randomized controlled trials, (b) RDCR implementation of at least 12 weeks duration, (c) assessment of safety, rates of serious adverse events (SAEs) and re-hospitalization incidences at endpoints more than 6 months. Three reviewers independently performed data extraction and assessed the risk of bias using the Cochrane Risk of Bias tool. Results 14 studies were identified involving 2012 participants and a range of RDCR duration between 3 months to 1 year. The incidence rate of exercise-related SAEs was estimated at 1 per 53,770 patient-hours of RDCR exercise. A non-statistically significant reduction in the re-hospitalization rates and the days lost due to hospitalization was noticed in the RDCR groups. There were no exercise-related deaths. The overall study quality was of low risk. Conclusions RDCR can act as a safe alternative delivery mode of cardiac rehabilitation (CR). The low long-term rates of reported SAEs and re-hospitalization incidences of the RDCR could enhance the uptake rates of CR interventions. However, further investigation is needed in larger populations and longer assessment points.
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spelling doaj.art-ed751d4d434b46418280388e5715d80b2024-03-26T10:03:24ZengSAGE PublishingDigital Health2055-20762024-03-011010.1177/20552076241237661Safety and long-term outcomes of remote cardiac rehabilitation in coronary heart disease patients: A systematic reviewVarsamo Antoniou0Eleni Kapreli1Constantinos H Davos2Ladislav Batalik3Garyfallia Pepera4 Clinical Exercise Physiology and Rehabilitation Laboratory, Department of Physiotherapy, School of Health Sciences, , Lamia, Greece Clinical Exercise Physiology and Rehabilitation Laboratory, Department of Physiotherapy, School of Health Sciences, , Lamia, Greece Cardiovascular Research Laboratory, Biomedical Research Foundation, , Athens, Greece Department of Physiotherapy and Rehabilitation, Faculty of Medicine, Masaryk University, Brno, Czech Republic Clinical Exercise Physiology and Rehabilitation Laboratory, Department of Physiotherapy, School of Health Sciences, , Lamia, GreeceObjective To systematically review the safety and the long-term mortality and morbidity risk-rates of the remotely-delivered cardiac rehabilitation (RDCR) interventions in coronary heart disease (CHD) patients. Methods The protocol was registered in the International Prospective Register of Systematic Reviews (CRD42023455471). Five databases (Pubmed, Scopus, Cochrane Central Register of Controlled Trials in the Cochrane Library, Cinahl and Web of Science) were reviewed from January 2012 up to August 2023. Inclusion criteria were: (a) randomized controlled trials, (b) RDCR implementation of at least 12 weeks duration, (c) assessment of safety, rates of serious adverse events (SAEs) and re-hospitalization incidences at endpoints more than 6 months. Three reviewers independently performed data extraction and assessed the risk of bias using the Cochrane Risk of Bias tool. Results 14 studies were identified involving 2012 participants and a range of RDCR duration between 3 months to 1 year. The incidence rate of exercise-related SAEs was estimated at 1 per 53,770 patient-hours of RDCR exercise. A non-statistically significant reduction in the re-hospitalization rates and the days lost due to hospitalization was noticed in the RDCR groups. There were no exercise-related deaths. The overall study quality was of low risk. Conclusions RDCR can act as a safe alternative delivery mode of cardiac rehabilitation (CR). The low long-term rates of reported SAEs and re-hospitalization incidences of the RDCR could enhance the uptake rates of CR interventions. However, further investigation is needed in larger populations and longer assessment points.https://doi.org/10.1177/20552076241237661
spellingShingle Varsamo Antoniou
Eleni Kapreli
Constantinos H Davos
Ladislav Batalik
Garyfallia Pepera
Safety and long-term outcomes of remote cardiac rehabilitation in coronary heart disease patients: A systematic review
Digital Health
title Safety and long-term outcomes of remote cardiac rehabilitation in coronary heart disease patients: A systematic review
title_full Safety and long-term outcomes of remote cardiac rehabilitation in coronary heart disease patients: A systematic review
title_fullStr Safety and long-term outcomes of remote cardiac rehabilitation in coronary heart disease patients: A systematic review
title_full_unstemmed Safety and long-term outcomes of remote cardiac rehabilitation in coronary heart disease patients: A systematic review
title_short Safety and long-term outcomes of remote cardiac rehabilitation in coronary heart disease patients: A systematic review
title_sort safety and long term outcomes of remote cardiac rehabilitation in coronary heart disease patients a systematic review
url https://doi.org/10.1177/20552076241237661
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