Cancer-associated fibroblasts and its derived exosomes: a new perspective for reshaping the tumor microenvironment

Cancer-associated fibroblasts and its derived exosomes: a new perspective for reshaping the tumor microenvironment

Abstract Cancer-associated fibroblasts (CAFs) are the most abundant stromal cells within the tumor microenvironment (TME). They extensively communicate with the other cells. Exosome-packed bioactive molecules derived from CAFs can reshape the TME by interacting with other cells and the extracellular...

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Bibliographic Details
Main Authors: Zhiwei Peng, Zhiwei Tong, Zihao Ren, Manping Ye, Kongwang Hu
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Molecular Medicine
Subjects:
Cancer-associated fibroblasts
Exosomes
Tumor microenvironment
Diagnosis
Therapy
Online Access:https://doi.org/10.1186/s10020-023-00665-y

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