Flumatinib plus venetoclax as an effective therapy for Philadelphia chromosome‐positive acute myeloid leukemia: A case report

Abstract Philadelphia chromosome‐positive acute myeloid leukemia (Ph + AML) is a rare type of AML with a low survival rate and poor prognosis. We first report a Ph + AML patient who remained in long‐term remission after the combination of flumatinib and venetoclax, which could provide corresponding...

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Main Authors: Si‐Man Huang, Tao Tao, Chao‐Ling Wan, Tian‐Mei Wu, Han‐Yu Cao, Yan Qiu, Xiang‐Dong Shen, Bin‐Ru Wang, Shuai‐Shuai Ge, Yan‐Yan Li, Tong‐Tong Zhang, Bing Wu, Sheng‐Li Xue
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.6688
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author Si‐Man Huang
Tao Tao
Chao‐Ling Wan
Tian‐Mei Wu
Han‐Yu Cao
Yan Qiu
Xiang‐Dong Shen
Bin‐Ru Wang
Shuai‐Shuai Ge
Yan‐Yan Li
Tong‐Tong Zhang
Bing Wu
Sheng‐Li Xue
author_facet Si‐Man Huang
Tao Tao
Chao‐Ling Wan
Tian‐Mei Wu
Han‐Yu Cao
Yan Qiu
Xiang‐Dong Shen
Bin‐Ru Wang
Shuai‐Shuai Ge
Yan‐Yan Li
Tong‐Tong Zhang
Bing Wu
Sheng‐Li Xue
author_sort Si‐Man Huang
collection DOAJ
description Abstract Philadelphia chromosome‐positive acute myeloid leukemia (Ph + AML) is a rare type of AML with a low survival rate and poor prognosis. We first report a Ph + AML patient who remained in long‐term remission after the combination of flumatinib and venetoclax, which could provide corresponding treatment ideas for clinical practice.
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spelling doaj.art-ed773244ff8842be89b88a44e8235d722023-03-01T07:50:56ZengWileyClinical Case Reports2050-09042023-01-01111n/an/a10.1002/ccr3.6688Flumatinib plus venetoclax as an effective therapy for Philadelphia chromosome‐positive acute myeloid leukemia: A case reportSi‐Man Huang0Tao Tao1Chao‐Ling Wan2Tian‐Mei Wu3Han‐Yu Cao4Yan Qiu5Xiang‐Dong Shen6Bin‐Ru Wang7Shuai‐Shuai Ge8Yan‐Yan Li9Tong‐Tong Zhang10Bing Wu11Sheng‐Li Xue12National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University Suzhou ChinaDepartment of Respiratory and Critical Medicine the Fifth People's Hospital of Suzhou Suzhou ChinaNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University Suzhou ChinaNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University Suzhou ChinaNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University Suzhou ChinaNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University Suzhou ChinaNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University Suzhou ChinaNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University Suzhou ChinaNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University Suzhou ChinaNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University Suzhou ChinaNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University Suzhou ChinaSuzhou Hospital of Chinese Traditional Medicine the Affiliated Hospital of Nanjing University of Chinese Traditional Medicine Suzhou ChinaNational Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University Suzhou ChinaAbstract Philadelphia chromosome‐positive acute myeloid leukemia (Ph + AML) is a rare type of AML with a low survival rate and poor prognosis. We first report a Ph + AML patient who remained in long‐term remission after the combination of flumatinib and venetoclax, which could provide corresponding treatment ideas for clinical practice.https://doi.org/10.1002/ccr3.6688flumatinibPhiladelphia chromosome‐positive acute myeloid leukemiaregimenvenetoclax
spellingShingle Si‐Man Huang
Tao Tao
Chao‐Ling Wan
Tian‐Mei Wu
Han‐Yu Cao
Yan Qiu
Xiang‐Dong Shen
Bin‐Ru Wang
Shuai‐Shuai Ge
Yan‐Yan Li
Tong‐Tong Zhang
Bing Wu
Sheng‐Li Xue
Flumatinib plus venetoclax as an effective therapy for Philadelphia chromosome‐positive acute myeloid leukemia: A case report
Clinical Case Reports
flumatinib
Philadelphia chromosome‐positive acute myeloid leukemia
regimen
venetoclax
title Flumatinib plus venetoclax as an effective therapy for Philadelphia chromosome‐positive acute myeloid leukemia: A case report
title_full Flumatinib plus venetoclax as an effective therapy for Philadelphia chromosome‐positive acute myeloid leukemia: A case report
title_fullStr Flumatinib plus venetoclax as an effective therapy for Philadelphia chromosome‐positive acute myeloid leukemia: A case report
title_full_unstemmed Flumatinib plus venetoclax as an effective therapy for Philadelphia chromosome‐positive acute myeloid leukemia: A case report
title_short Flumatinib plus venetoclax as an effective therapy for Philadelphia chromosome‐positive acute myeloid leukemia: A case report
title_sort flumatinib plus venetoclax as an effective therapy for philadelphia chromosome positive acute myeloid leukemia a case report
topic flumatinib
Philadelphia chromosome‐positive acute myeloid leukemia
regimen
venetoclax
url https://doi.org/10.1002/ccr3.6688
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