Targeted analysis of genomic regions enriched in African ancestry reveals novel classical HLA alleles associated with asthma in Southwestern Europeans

Targeted analysis of genomic regions enriched in African ancestry reveals novel classical HLA alleles associated with asthma in Southwestern Europeans

Abstract Despite asthma has a considerable genetic component, an important proportion of genetic risks remain unknown, especially for non-European populations. Canary Islanders have the largest African genetic ancestry observed among Southwestern Europeans and the highest asthma prevalence in Spain....

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Bibliographic Details
Main Authors: Eva Suarez-Pajes, Claudio Díaz-García, Héctor Rodríguez-Pérez, Jose M. Lorenzo-Salazar, Itahisa Marcelino-Rodríguez, Almudena Corrales, Xiuwen Zheng, Ariel Callero, Eva Perez-Rodriguez, Jose C. Garcia-Robaina, Rafaela González-Montelongo, Carlos Flores, Beatriz Guillen-Guio
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-02893-w

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