Establishment of a non-integrate iPS cell line (SDQLCHi023-A) from a patient with Xq25 microduplication syndrome carrying a 1.3 Mb hemizygote duplication at chrXq25
Xq25 microduplication syndrome is a recognized syndrome presenting intellectual disability and distinctive facial appearance. We generated an induced pluripotent stem cell (iPSC) line from peripheral blood mononuclear cells (PBMCs) of an 8-year-old boy with Xq25 Microduplication Syndrome carrying a...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-03-01
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| Series: | Stem Cell Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506120304487 |
| _version_ | 1818959531039784960 |
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| author | Xiaomeng Yang Chunhong Duan Haiyan Zhang Yue Li Jingyun Guan Dong Wang Yuqiang Lv Zhongtao Gai Yi Liu |
| author_facet | Xiaomeng Yang Chunhong Duan Haiyan Zhang Yue Li Jingyun Guan Dong Wang Yuqiang Lv Zhongtao Gai Yi Liu |
| author_sort | Xiaomeng Yang |
| collection | DOAJ |
| description | Xq25 microduplication syndrome is a recognized syndrome presenting intellectual disability and distinctive facial appearance. We generated an induced pluripotent stem cell (iPSC) line from peripheral blood mononuclear cells (PBMCs) of an 8-year-old boy with Xq25 Microduplication Syndrome carrying a 1.3 Mb hemizygote duplication at chrXq25. The iPSCs expressed pluripotency markers, free of genomically integrated episomal plasmids, with normal karyotype and three layers’ differentiation potential in vitro. |
| first_indexed | 2024-12-20T11:43:07Z |
| format | Article |
| id | doaj.art-ed797b5a7d7c4f879122ad8ff9d1c7c0 |
| institution | Directory Open Access Journal |
| issn | 1873-5061 |
| language | English |
| last_indexed | 2024-12-20T11:43:07Z |
| publishDate | 2021-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Stem Cell Research |
| spelling | doaj.art-ed797b5a7d7c4f879122ad8ff9d1c7c02022-12-21T19:41:56ZengElsevierStem Cell Research1873-50612021-03-0151102147Establishment of a non-integrate iPS cell line (SDQLCHi023-A) from a patient with Xq25 microduplication syndrome carrying a 1.3 Mb hemizygote duplication at chrXq25Xiaomeng Yang0Chunhong Duan1Haiyan Zhang2Yue Li3Jingyun Guan4Dong Wang5Yuqiang Lv6Zhongtao Gai7Yi Liu8Pediatric Research Institute, Qilu Children’s Hospital of Shandong University, Jinan, Shandong 250022, ChinaDepartment of Pediatrics, Qilu Children’s Hospital of Shandong University, Jinan, Shandong 250022, ChinaPediatric Research Institute, Qilu Children’s Hospital of Shandong University, Jinan, Shandong 250022, ChinaPediatric Research Institute, Qilu Children’s Hospital of Shandong University, Jinan, Shandong 250022, ChinaPediatric Research Institute, Qilu Children’s Hospital of Shandong University, Jinan, Shandong 250022, ChinaPediatric Research Institute, Qilu Children’s Hospital of Shandong University, Jinan, Shandong 250022, ChinaPediatric Research Institute, Qilu Children’s Hospital of Shandong University, Jinan, Shandong 250022, ChinaPediatric Research Institute, Qilu Children’s Hospital of Shandong University, Jinan, Shandong 250022, China; Corresponding authors.Pediatric Research Institute, Qilu Children’s Hospital of Shandong University, Jinan, Shandong 250022, China; Corresponding authors.Xq25 microduplication syndrome is a recognized syndrome presenting intellectual disability and distinctive facial appearance. We generated an induced pluripotent stem cell (iPSC) line from peripheral blood mononuclear cells (PBMCs) of an 8-year-old boy with Xq25 Microduplication Syndrome carrying a 1.3 Mb hemizygote duplication at chrXq25. The iPSCs expressed pluripotency markers, free of genomically integrated episomal plasmids, with normal karyotype and three layers’ differentiation potential in vitro.http://www.sciencedirect.com/science/article/pii/S1873506120304487 |
| spellingShingle | Xiaomeng Yang Chunhong Duan Haiyan Zhang Yue Li Jingyun Guan Dong Wang Yuqiang Lv Zhongtao Gai Yi Liu Establishment of a non-integrate iPS cell line (SDQLCHi023-A) from a patient with Xq25 microduplication syndrome carrying a 1.3 Mb hemizygote duplication at chrXq25 Stem Cell Research |
| title | Establishment of a non-integrate iPS cell line (SDQLCHi023-A) from a patient with Xq25 microduplication syndrome carrying a 1.3 Mb hemizygote duplication at chrXq25 |
| title_full | Establishment of a non-integrate iPS cell line (SDQLCHi023-A) from a patient with Xq25 microduplication syndrome carrying a 1.3 Mb hemizygote duplication at chrXq25 |
| title_fullStr | Establishment of a non-integrate iPS cell line (SDQLCHi023-A) from a patient with Xq25 microduplication syndrome carrying a 1.3 Mb hemizygote duplication at chrXq25 |
| title_full_unstemmed | Establishment of a non-integrate iPS cell line (SDQLCHi023-A) from a patient with Xq25 microduplication syndrome carrying a 1.3 Mb hemizygote duplication at chrXq25 |
| title_short | Establishment of a non-integrate iPS cell line (SDQLCHi023-A) from a patient with Xq25 microduplication syndrome carrying a 1.3 Mb hemizygote duplication at chrXq25 |
| title_sort | establishment of a non integrate ips cell line sdqlchi023 a from a patient with xq25 microduplication syndrome carrying a 1 3 mb hemizygote duplication at chrxq25 |
| url | http://www.sciencedirect.com/science/article/pii/S1873506120304487 |
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