Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era
Context: Due to its unique paternal inheritance, the Y-chromosome has been a highly popular marker among population geneticists for over two decades. Recently, the advent of cost-effective genome-wide methods has unlocked information-rich autosomal genomic data, paving the way to the postgenomic era...
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Format: | Article |
Language: | English |
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Taylor & Francis Group
2018-01-01
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Series: | Annals of Human Biology |
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Online Access: | http://dx.doi.org/10.1080/03014460.2017.1402956 |
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author | Maarten H. D. Larmuseau Claudio Ottoni |
author_facet | Maarten H. D. Larmuseau Claudio Ottoni |
author_sort | Maarten H. D. Larmuseau |
collection | DOAJ |
description | Context: Due to its unique paternal inheritance, the Y-chromosome has been a highly popular marker among population geneticists for over two decades. Recently, the advent of cost-effective genome-wide methods has unlocked information-rich autosomal genomic data, paving the way to the postgenomic era. This seems to have announced the decreasing popularity of investigating Y-chromosome variation, which provides only the paternal perspective of human ancestries and is strongly influenced by genetic drift and social behaviour. Objective: For this special issue on population genetics of the Mediterranean, the aim was to demonstrate that the Y-chromosome still provides important insights in the postgenomic era and in a time when ancient genomes are becoming exponentially available. Methods: A systematic literature search on Y-chromosomal studies in the Mediterranean was performed. Results: Several applications of Y-chromosomal analysis with future opportunities are formulated and illustrated with studies on Mediterranean populations. Conclusions: There will be no reduced interest in Y-chromosomal studies going from reconstruction of male-specific demographic events to ancient DNA applications, surname history and population-wide estimations of extra-pair paternity rates. Moreover, more initiatives are required to collect population genetic data of Y-chromosomal markers for forensic research, and to include Y-chromosomal data in GWAS investigations and studies on male infertility. |
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id | doaj.art-ed7d91b4b04e47a79bafc30a6829ae09 |
institution | Directory Open Access Journal |
issn | 0301-4460 1464-5033 |
language | English |
last_indexed | 2024-03-12T00:47:34Z |
publishDate | 2018-01-01 |
publisher | Taylor & Francis Group |
record_format | Article |
series | Annals of Human Biology |
spelling | doaj.art-ed7d91b4b04e47a79bafc30a6829ae092023-09-14T15:36:09ZengTaylor & Francis GroupAnnals of Human Biology0301-44601464-50332018-01-01451203310.1080/03014460.2017.14029561402956Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic eraMaarten H. D. Larmuseau0Claudio Ottoni1KU Leuven, Forensic Biomedical SciencesUniversity of OsloContext: Due to its unique paternal inheritance, the Y-chromosome has been a highly popular marker among population geneticists for over two decades. Recently, the advent of cost-effective genome-wide methods has unlocked information-rich autosomal genomic data, paving the way to the postgenomic era. This seems to have announced the decreasing popularity of investigating Y-chromosome variation, which provides only the paternal perspective of human ancestries and is strongly influenced by genetic drift and social behaviour. Objective: For this special issue on population genetics of the Mediterranean, the aim was to demonstrate that the Y-chromosome still provides important insights in the postgenomic era and in a time when ancient genomes are becoming exponentially available. Methods: A systematic literature search on Y-chromosomal studies in the Mediterranean was performed. Results: Several applications of Y-chromosomal analysis with future opportunities are formulated and illustrated with studies on Mediterranean populations. Conclusions: There will be no reduced interest in Y-chromosomal studies going from reconstruction of male-specific demographic events to ancient DNA applications, surname history and population-wide estimations of extra-pair paternity rates. Moreover, more initiatives are required to collect population genetic data of Y-chromosomal markers for forensic research, and to include Y-chromosomal data in GWAS investigations and studies on male infertility.http://dx.doi.org/10.1080/03014460.2017.1402956y-chromosomemediterraneanpopulation geneticsforensicssurnamesextra-pair paternity |
spellingShingle | Maarten H. D. Larmuseau Claudio Ottoni Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era Annals of Human Biology y-chromosome mediterranean population genetics forensics surnames extra-pair paternity |
title | Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era |
title_full | Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era |
title_fullStr | Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era |
title_full_unstemmed | Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era |
title_short | Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era |
title_sort | mediterranean y chromosome 2 0 why the y in the mediterranean is still relevant in the postgenomic era |
topic | y-chromosome mediterranean population genetics forensics surnames extra-pair paternity |
url | http://dx.doi.org/10.1080/03014460.2017.1402956 |
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