Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era

Context: Due to its unique paternal inheritance, the Y-chromosome has been a highly popular marker among population geneticists for over two decades. Recently, the advent of cost-effective genome-wide methods has unlocked information-rich autosomal genomic data, paving the way to the postgenomic era...

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Main Authors: Maarten H. D. Larmuseau, Claudio Ottoni
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Annals of Human Biology
Subjects:
Online Access:http://dx.doi.org/10.1080/03014460.2017.1402956
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author Maarten H. D. Larmuseau
Claudio Ottoni
author_facet Maarten H. D. Larmuseau
Claudio Ottoni
author_sort Maarten H. D. Larmuseau
collection DOAJ
description Context: Due to its unique paternal inheritance, the Y-chromosome has been a highly popular marker among population geneticists for over two decades. Recently, the advent of cost-effective genome-wide methods has unlocked information-rich autosomal genomic data, paving the way to the postgenomic era. This seems to have announced the decreasing popularity of investigating Y-chromosome variation, which provides only the paternal perspective of human ancestries and is strongly influenced by genetic drift and social behaviour. Objective: For this special issue on population genetics of the Mediterranean, the aim was to demonstrate that the Y-chromosome still provides important insights in the postgenomic era and in a time when ancient genomes are becoming exponentially available. Methods: A systematic literature search on Y-chromosomal studies in the Mediterranean was performed. Results: Several applications of Y-chromosomal analysis with future opportunities are formulated and illustrated with studies on Mediterranean populations. Conclusions: There will be no reduced interest in Y-chromosomal studies going from reconstruction of male-specific demographic events to ancient DNA applications, surname history and population-wide estimations of extra-pair paternity rates. Moreover, more initiatives are required to collect population genetic data of Y-chromosomal markers for forensic research, and to include Y-chromosomal data in GWAS investigations and studies on male infertility.
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spelling doaj.art-ed7d91b4b04e47a79bafc30a6829ae092023-09-14T15:36:09ZengTaylor & Francis GroupAnnals of Human Biology0301-44601464-50332018-01-01451203310.1080/03014460.2017.14029561402956Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic eraMaarten H. D. Larmuseau0Claudio Ottoni1KU Leuven, Forensic Biomedical SciencesUniversity of OsloContext: Due to its unique paternal inheritance, the Y-chromosome has been a highly popular marker among population geneticists for over two decades. Recently, the advent of cost-effective genome-wide methods has unlocked information-rich autosomal genomic data, paving the way to the postgenomic era. This seems to have announced the decreasing popularity of investigating Y-chromosome variation, which provides only the paternal perspective of human ancestries and is strongly influenced by genetic drift and social behaviour. Objective: For this special issue on population genetics of the Mediterranean, the aim was to demonstrate that the Y-chromosome still provides important insights in the postgenomic era and in a time when ancient genomes are becoming exponentially available. Methods: A systematic literature search on Y-chromosomal studies in the Mediterranean was performed. Results: Several applications of Y-chromosomal analysis with future opportunities are formulated and illustrated with studies on Mediterranean populations. Conclusions: There will be no reduced interest in Y-chromosomal studies going from reconstruction of male-specific demographic events to ancient DNA applications, surname history and population-wide estimations of extra-pair paternity rates. Moreover, more initiatives are required to collect population genetic data of Y-chromosomal markers for forensic research, and to include Y-chromosomal data in GWAS investigations and studies on male infertility.http://dx.doi.org/10.1080/03014460.2017.1402956y-chromosomemediterraneanpopulation geneticsforensicssurnamesextra-pair paternity
spellingShingle Maarten H. D. Larmuseau
Claudio Ottoni
Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era
Annals of Human Biology
y-chromosome
mediterranean
population genetics
forensics
surnames
extra-pair paternity
title Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era
title_full Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era
title_fullStr Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era
title_full_unstemmed Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era
title_short Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era
title_sort mediterranean y chromosome 2 0 why the y in the mediterranean is still relevant in the postgenomic era
topic y-chromosome
mediterranean
population genetics
forensics
surnames
extra-pair paternity
url http://dx.doi.org/10.1080/03014460.2017.1402956
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