Effect of intraoperative lidocaine on anesthetic consumption, and bowel function, pain intensity, analgesic consumption and hospital stay after breast surgery

BackgroundPerioperative lidocaine infusion improves postoperative outcomes, mostly after abdominal and urologic surgeries. Knowledge of the effect of lidocaine on peripheral surgeries is limited. Presently, we investigated whether intraoperative lidocaine infusion reduced anesthetic consumption, dur...

Full description

Bibliographic Details
Main Authors: Soo Joo Choi, Myung Hee Kim, Hui Yeon Jeong, Jeong Jin Lee
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2012-05-01
Series:Korean Journal of Anesthesiology
Subjects:
Online Access:http://ekja.org/upload/pdf/kjae-62-429.pdf
_version_ 1818890876831662080
author Soo Joo Choi
Myung Hee Kim
Hui Yeon Jeong
Jeong Jin Lee
author_facet Soo Joo Choi
Myung Hee Kim
Hui Yeon Jeong
Jeong Jin Lee
author_sort Soo Joo Choi
collection DOAJ
description BackgroundPerioperative lidocaine infusion improves postoperative outcomes, mostly after abdominal and urologic surgeries. Knowledge of the effect of lidocaine on peripheral surgeries is limited. Presently, we investigated whether intraoperative lidocaine infusion reduced anesthetic consumption, duration of ileus, pain intensity, analgesic consumption and hospital stay after breast plastic surgeries.MethodsSixty female patients, aged 20-60 years, enrolled in this prospective study were randomly and equally divided to two groups. One group (n = 30) received a 1.5 mg/kg bolus of lidocaine approximately 30 min before incision followed by continuous infusion of lidocaine (1.5 mg/kg/h) until skin closure (lidocaine group). The other group (n = 30) was untreated (control group). Balanced inhalation (sevoflurane) anesthesia and multimodal postoperative analgesia were standardized. End tidal sevoflurane concentration during surgery, time to the first flatus and defecation, visual analog pain scale (0-10), analgesic consumption and associated side effects at 24, 48, and 72 h after surgery, hospital stay, and patient's general satisfaction were assessed.ResultsCompared to the control group, intraoperative lidocaine infusion reduced by 5% the amount of sevoflurane required at similar bispectral index (P = 0.014). However, there were no significant effects of lidocaine regarding the return of bowel function, postoperative pain intensity, analgesic sparing and side effects at all time points, hospital stay, and level of patient's satisfaction for pain control.ConclusionsLow dose intraoperative lidocaine infusion offered no beneficial effects on return of bowel function, opioid sparing, pain intensity and hospital stay after various breast plastic surgeries.
first_indexed 2024-12-19T17:31:53Z
format Article
id doaj.art-ed85e3b77000468ca541198a7eeed58e
institution Directory Open Access Journal
issn 2005-6419
2005-7563
language English
last_indexed 2024-12-19T17:31:53Z
publishDate 2012-05-01
publisher Korean Society of Anesthesiologists
record_format Article
series Korean Journal of Anesthesiology
spelling doaj.art-ed85e3b77000468ca541198a7eeed58e2022-12-21T20:12:26ZengKorean Society of AnesthesiologistsKorean Journal of Anesthesiology2005-64192005-75632012-05-0162542943410.4097/kjae.2012.62.5.4297335Effect of intraoperative lidocaine on anesthetic consumption, and bowel function, pain intensity, analgesic consumption and hospital stay after breast surgerySoo Joo Choi0Myung Hee Kim1Hui Yeon Jeong2Jeong Jin Lee3Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.BackgroundPerioperative lidocaine infusion improves postoperative outcomes, mostly after abdominal and urologic surgeries. Knowledge of the effect of lidocaine on peripheral surgeries is limited. Presently, we investigated whether intraoperative lidocaine infusion reduced anesthetic consumption, duration of ileus, pain intensity, analgesic consumption and hospital stay after breast plastic surgeries.MethodsSixty female patients, aged 20-60 years, enrolled in this prospective study were randomly and equally divided to two groups. One group (n = 30) received a 1.5 mg/kg bolus of lidocaine approximately 30 min before incision followed by continuous infusion of lidocaine (1.5 mg/kg/h) until skin closure (lidocaine group). The other group (n = 30) was untreated (control group). Balanced inhalation (sevoflurane) anesthesia and multimodal postoperative analgesia were standardized. End tidal sevoflurane concentration during surgery, time to the first flatus and defecation, visual analog pain scale (0-10), analgesic consumption and associated side effects at 24, 48, and 72 h after surgery, hospital stay, and patient's general satisfaction were assessed.ResultsCompared to the control group, intraoperative lidocaine infusion reduced by 5% the amount of sevoflurane required at similar bispectral index (P = 0.014). However, there were no significant effects of lidocaine regarding the return of bowel function, postoperative pain intensity, analgesic sparing and side effects at all time points, hospital stay, and level of patient's satisfaction for pain control.ConclusionsLow dose intraoperative lidocaine infusion offered no beneficial effects on return of bowel function, opioid sparing, pain intensity and hospital stay after various breast plastic surgeries.http://ekja.org/upload/pdf/kjae-62-429.pdfanalgesic consumptionanesthetic consumptionbowel functionhospital stayintravenous lidocainepain score
spellingShingle Soo Joo Choi
Myung Hee Kim
Hui Yeon Jeong
Jeong Jin Lee
Effect of intraoperative lidocaine on anesthetic consumption, and bowel function, pain intensity, analgesic consumption and hospital stay after breast surgery
Korean Journal of Anesthesiology
analgesic consumption
anesthetic consumption
bowel function
hospital stay
intravenous lidocaine
pain score
title Effect of intraoperative lidocaine on anesthetic consumption, and bowel function, pain intensity, analgesic consumption and hospital stay after breast surgery
title_full Effect of intraoperative lidocaine on anesthetic consumption, and bowel function, pain intensity, analgesic consumption and hospital stay after breast surgery
title_fullStr Effect of intraoperative lidocaine on anesthetic consumption, and bowel function, pain intensity, analgesic consumption and hospital stay after breast surgery
title_full_unstemmed Effect of intraoperative lidocaine on anesthetic consumption, and bowel function, pain intensity, analgesic consumption and hospital stay after breast surgery
title_short Effect of intraoperative lidocaine on anesthetic consumption, and bowel function, pain intensity, analgesic consumption and hospital stay after breast surgery
title_sort effect of intraoperative lidocaine on anesthetic consumption and bowel function pain intensity analgesic consumption and hospital stay after breast surgery
topic analgesic consumption
anesthetic consumption
bowel function
hospital stay
intravenous lidocaine
pain score
url http://ekja.org/upload/pdf/kjae-62-429.pdf
work_keys_str_mv AT soojoochoi effectofintraoperativelidocaineonanestheticconsumptionandbowelfunctionpainintensityanalgesicconsumptionandhospitalstayafterbreastsurgery
AT myungheekim effectofintraoperativelidocaineonanestheticconsumptionandbowelfunctionpainintensityanalgesicconsumptionandhospitalstayafterbreastsurgery
AT huiyeonjeong effectofintraoperativelidocaineonanestheticconsumptionandbowelfunctionpainintensityanalgesicconsumptionandhospitalstayafterbreastsurgery
AT jeongjinlee effectofintraoperativelidocaineonanestheticconsumptionandbowelfunctionpainintensityanalgesicconsumptionandhospitalstayafterbreastsurgery