Immunomodulatory effect of two hydrolysates of chitin on cyclophosphamide-induced mice via immune response enhancement and gut microbiota modulation

In this study, the hydrolysis products of chitin, COS1 and COS2, had degrees of deacetylation of 5.9% and 85.7%, respectively. Notably, 50 mg/(kg·d) COS1 and COS2 significantly increased the levels of immunoglobulins (IgG and IgM), cytokines (IL-6 and IFN-γ), and the antioxidant activities (SOD and...

Full description

Bibliographic Details
Main Authors: Qiao Zhang, Xiaoxian Tang, Xueying Zhang, Yuanchang He, Yongcheng Li
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623003997