The contribution of the basal ganglia and cerebellum to motor learning: A neuro-computational approach.
Motor learning involves a widespread brain network including the basal ganglia, cerebellum, motor cortex, and brainstem. Despite its importance, little is known about how this network learns motor tasks and which role different parts of this network take. We designed a systems-level computational mo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2023-04-01
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| Series: | PLoS Computational Biology |
| Online Access: | https://doi.org/10.1371/journal.pcbi.1011024 |
| _version_ | 1827917612591349760 |
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| author | Javier Baladron Julien Vitay Torsten Fietzek Fred H Hamker |
| author_facet | Javier Baladron Julien Vitay Torsten Fietzek Fred H Hamker |
| author_sort | Javier Baladron |
| collection | DOAJ |
| description | Motor learning involves a widespread brain network including the basal ganglia, cerebellum, motor cortex, and brainstem. Despite its importance, little is known about how this network learns motor tasks and which role different parts of this network take. We designed a systems-level computational model of motor learning, including a cortex-basal ganglia motor loop and the cerebellum that both determine the response of central pattern generators in the brainstem. First, we demonstrate its ability to learn arm movements toward different motor goals. Second, we test the model in a motor adaptation task with cognitive control, where the model replicates human data. We conclude that the cortex-basal ganglia loop learns via a novelty-based motor prediction error to determine concrete actions given a desired outcome, and that the cerebellum minimizes the remaining aiming error. |
| first_indexed | 2024-03-13T03:30:53Z |
| format | Article |
| id | doaj.art-ed904378eee64d36afb595bb11c9fe38 |
| institution | Directory Open Access Journal |
| issn | 1553-734X 1553-7358 |
| language | English |
| last_indexed | 2024-03-13T03:30:53Z |
| publishDate | 2023-04-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Computational Biology |
| spelling | doaj.art-ed904378eee64d36afb595bb11c9fe382023-06-24T05:31:05ZengPublic Library of Science (PLoS)PLoS Computational Biology1553-734X1553-73582023-04-01194e101102410.1371/journal.pcbi.1011024The contribution of the basal ganglia and cerebellum to motor learning: A neuro-computational approach.Javier BaladronJulien VitayTorsten FietzekFred H HamkerMotor learning involves a widespread brain network including the basal ganglia, cerebellum, motor cortex, and brainstem. Despite its importance, little is known about how this network learns motor tasks and which role different parts of this network take. We designed a systems-level computational model of motor learning, including a cortex-basal ganglia motor loop and the cerebellum that both determine the response of central pattern generators in the brainstem. First, we demonstrate its ability to learn arm movements toward different motor goals. Second, we test the model in a motor adaptation task with cognitive control, where the model replicates human data. We conclude that the cortex-basal ganglia loop learns via a novelty-based motor prediction error to determine concrete actions given a desired outcome, and that the cerebellum minimizes the remaining aiming error.https://doi.org/10.1371/journal.pcbi.1011024 |
| spellingShingle | Javier Baladron Julien Vitay Torsten Fietzek Fred H Hamker The contribution of the basal ganglia and cerebellum to motor learning: A neuro-computational approach. PLoS Computational Biology |
| title | The contribution of the basal ganglia and cerebellum to motor learning: A neuro-computational approach. |
| title_full | The contribution of the basal ganglia and cerebellum to motor learning: A neuro-computational approach. |
| title_fullStr | The contribution of the basal ganglia and cerebellum to motor learning: A neuro-computational approach. |
| title_full_unstemmed | The contribution of the basal ganglia and cerebellum to motor learning: A neuro-computational approach. |
| title_short | The contribution of the basal ganglia and cerebellum to motor learning: A neuro-computational approach. |
| title_sort | contribution of the basal ganglia and cerebellum to motor learning a neuro computational approach |
| url | https://doi.org/10.1371/journal.pcbi.1011024 |
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