A pre-anesthetic bolus of ketamine versus dexmedetomidine for prevention of postoperative delirium in elderly patients undergoing emergency surgery: a randomized, double-blinded, placebo-controlled study

A pre-anesthetic bolus of ketamine versus dexmedetomidine for prevention of postoperative delirium in elderly patients undergoing emergency surgery: a randomized, double-blinded, placebo-controlled study

Abstract Background We aimed to evaluate whether a single dose of ketamine or dexmedetomidine before induction of general anesthesia could reduce the incidence of postoperative delirium (primary outcome) or cognitive dysfunction (secondary outcome) in elderly patients undergoing emergency surgery. P...

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Bibliographic Details
Main Authors: Huda F. Ghazaly, Tarek S. Hemaida, Zaher Z. Zaher, Omar M. Elkhodary, Soudy S. Hammad
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Anesthesiology
Subjects:
Dexmedetomidine
Elderly patients
Emergency surgery
Ketamine
Postoperative delirium
Online Access:https://doi.org/10.1186/s12871-023-02367-8

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