Sexual steroids and functions of the brain
Neurosteroids are endogenous modulators of nervous excitability. There is increasing evidence of sedative, anxiolytic, analgesic and anticonvulsant properties of neurosteroids. Progesterone and allopregnanolol participate in adaptation to stress, and also have immunomodulating activity and cytoprote...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
IP Berlin A.V.
2017-04-01
|
| Series: | Гинекология |
| Subjects: | |
| Online Access: | https://gynecology.orscience.ru/2079-5831/article/viewFile/28600/pdf |
| _version_ | 1819155200714211328 |
|---|---|
| author | N N Stenyaeva D F Chritinin V Yu Grigoriev A A Kusemin |
| author_facet | N N Stenyaeva D F Chritinin V Yu Grigoriev A A Kusemin |
| author_sort | N N Stenyaeva |
| collection | DOAJ |
| description | Neurosteroids are endogenous modulators of nervous excitability. There is increasing evidence of sedative, anxiolytic, analgesic and anticonvulsant properties of neurosteroids. Progesterone and allopregnanolol participate in adaptation to stress, and also have immunomodulating activity and cytoprotective properties. Neurosteroids have the potential therapeutic possibilities associated with molecular mechanisms of the epileptogenesis interruption and modulation of neuroinflammation and neurogenesis in the brain. |
| first_indexed | 2024-12-22T15:33:12Z |
| format | Article |
| id | doaj.art-ed92cddd39c14ce98f87512b6e55f26e |
| institution | Directory Open Access Journal |
| issn | 2079-5696 2079-5831 |
| language | Russian |
| last_indexed | 2024-12-22T15:33:12Z |
| publishDate | 2017-04-01 |
| publisher | IP Berlin A.V. |
| record_format | Article |
| series | Гинекология |
| spelling | doaj.art-ed92cddd39c14ce98f87512b6e55f26e2022-12-21T18:21:19ZrusIP Berlin A.V.Гинекология2079-56962079-58312017-04-0119291425730Sexual steroids and functions of the brainN N Stenyaeva0D F Chritinin1V Yu Grigoriev2A A Kusemin3Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian FederationI.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationI.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationResearch Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian FederationNeurosteroids are endogenous modulators of nervous excitability. There is increasing evidence of sedative, anxiolytic, analgesic and anticonvulsant properties of neurosteroids. Progesterone and allopregnanolol participate in adaptation to stress, and also have immunomodulating activity and cytoprotective properties. Neurosteroids have the potential therapeutic possibilities associated with molecular mechanisms of the epileptogenesis interruption and modulation of neuroinflammation and neurogenesis in the brain.https://gynecology.orscience.ru/2079-5831/article/viewFile/28600/pdfneurosteroidsprogesteronebrainstressdepressionneuroinflammation |
| spellingShingle | N N Stenyaeva D F Chritinin V Yu Grigoriev A A Kusemin Sexual steroids and functions of the brain Гинекология neurosteroids progesterone brain stress depression neuroinflammation |
| title | Sexual steroids and functions of the brain |
| title_full | Sexual steroids and functions of the brain |
| title_fullStr | Sexual steroids and functions of the brain |
| title_full_unstemmed | Sexual steroids and functions of the brain |
| title_short | Sexual steroids and functions of the brain |
| title_sort | sexual steroids and functions of the brain |
| topic | neurosteroids progesterone brain stress depression neuroinflammation |
| url | https://gynecology.orscience.ru/2079-5831/article/viewFile/28600/pdf |
| work_keys_str_mv | AT nnstenyaeva sexualsteroidsandfunctionsofthebrain AT dfchritinin sexualsteroidsandfunctionsofthebrain AT vyugrigoriev sexualsteroidsandfunctionsofthebrain AT aakusemin sexualsteroidsandfunctionsofthebrain |