Daytime napping, biological aging and cognitive function among middle-aged and older Chinese: insights from the China health and retirement longitudinal study
ObjectiveThe complicated association of daytime napping, biological aging and cognitive function remains inconclusive. We aimed to evaluate the cross-sectional and longitudinal associations of daytime napping and two aging measures with cognition and to examine whether napping affects cognition thro...
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| Format: | Article |
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Frontiers Media S.A.
2023-11-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1294948/full |
| _version_ | 1827738805615984640 |
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| author | Huiyi Wu Lei Huang Shushan Zhang Yang Zhang Yang Zhang Yajia Lan |
| author_facet | Huiyi Wu Lei Huang Shushan Zhang Yang Zhang Yang Zhang Yajia Lan |
| author_sort | Huiyi Wu |
| collection | DOAJ |
| description | ObjectiveThe complicated association of daytime napping, biological aging and cognitive function remains inconclusive. We aimed to evaluate the cross-sectional and longitudinal associations of daytime napping and two aging measures with cognition and to examine whether napping affects cognition through a more advanced state of aging.MethodsData was collected from the China Health and Retirement Longitudinal Study. Napping was self-reported. We calculated two published biological aging measures: Klemera and Doubal biological age (KDM-BA) and physiological dysregulation (PD), which derived information from clinical biomarkers. Cognitive z-scores were calculated at each wave. Linear mixed models were used to explore the longitudinal association between napping, two aging measures, and cognitive decline. Mediation analyses were performed to assess the mediating effects of biological age acceleration on the association between napping and cognition.ResultsParticipants aged over 45 years were included in the analyses. Non-nappers had greater KDM-BA and PD [LS means (LSM) = 0.255, p = 0.007; LSM = 0.085, p = 0.011] and faster cognitive decline (LSM = −0.061, p = 0.005)compared to moderate nappers (30–90 min/nap). KDM-BA (β = −0.007, p = 0.018) and PD (β = −0.034, p < 0.001) showed a negative association with overall cognitive z scores. KDM-BA and PD partially mediated the effect of napping on cognition.ConclusionIn middle-aged and older Chinese, compared to moderate nappers, non-nappers seem to experience a more advanced state of aging and increased rates of cognitive decline. The aging status possibly mediates the association between napping and cognition. Moderate napping shows promise in promoting healthy aging and reducing the burden of cognitive decline in Chinese middle-aged and older adults. |
| first_indexed | 2024-03-11T02:50:12Z |
| format | Article |
| id | doaj.art-ed969f8e09bd4d3aa8651e94f4f36b72 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-03-11T02:50:12Z |
| publishDate | 2023-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-ed969f8e09bd4d3aa8651e94f4f36b722023-11-18T09:06:06ZengFrontiers Media S.A.Frontiers in Public Health2296-25652023-11-011110.3389/fpubh.2023.12949481294948Daytime napping, biological aging and cognitive function among middle-aged and older Chinese: insights from the China health and retirement longitudinal studyHuiyi Wu0Lei Huang1Shushan Zhang2Yang Zhang3Yang Zhang4Yajia Lan5Department of Epidemiology and Biostatistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, ChinaWest China Hospital/West China School of Medicine, Sichuan University, Chengdu, ChinaDepartment of Neurology, Affiliated Hospital of North Sichuan Medical College, Nanchong, ChinaDepartment of Periodical Press and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, ChinaChinese Evidence-Based Medicine Center, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Environmental Health and Occupational Medicine, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, ChinaObjectiveThe complicated association of daytime napping, biological aging and cognitive function remains inconclusive. We aimed to evaluate the cross-sectional and longitudinal associations of daytime napping and two aging measures with cognition and to examine whether napping affects cognition through a more advanced state of aging.MethodsData was collected from the China Health and Retirement Longitudinal Study. Napping was self-reported. We calculated two published biological aging measures: Klemera and Doubal biological age (KDM-BA) and physiological dysregulation (PD), which derived information from clinical biomarkers. Cognitive z-scores were calculated at each wave. Linear mixed models were used to explore the longitudinal association between napping, two aging measures, and cognitive decline. Mediation analyses were performed to assess the mediating effects of biological age acceleration on the association between napping and cognition.ResultsParticipants aged over 45 years were included in the analyses. Non-nappers had greater KDM-BA and PD [LS means (LSM) = 0.255, p = 0.007; LSM = 0.085, p = 0.011] and faster cognitive decline (LSM = −0.061, p = 0.005)compared to moderate nappers (30–90 min/nap). KDM-BA (β = −0.007, p = 0.018) and PD (β = −0.034, p < 0.001) showed a negative association with overall cognitive z scores. KDM-BA and PD partially mediated the effect of napping on cognition.ConclusionIn middle-aged and older Chinese, compared to moderate nappers, non-nappers seem to experience a more advanced state of aging and increased rates of cognitive decline. The aging status possibly mediates the association between napping and cognition. Moderate napping shows promise in promoting healthy aging and reducing the burden of cognitive decline in Chinese middle-aged and older adults.https://www.frontiersin.org/articles/10.3389/fpubh.2023.1294948/fullcognitive agingAlzheimer’s diseaseneurodegenerative diseaselongevitygerosciencebiological aging |
| spellingShingle | Huiyi Wu Lei Huang Shushan Zhang Yang Zhang Yang Zhang Yajia Lan Daytime napping, biological aging and cognitive function among middle-aged and older Chinese: insights from the China health and retirement longitudinal study Frontiers in Public Health cognitive aging Alzheimer’s disease neurodegenerative disease longevity geroscience biological aging |
| title | Daytime napping, biological aging and cognitive function among middle-aged and older Chinese: insights from the China health and retirement longitudinal study |
| title_full | Daytime napping, biological aging and cognitive function among middle-aged and older Chinese: insights from the China health and retirement longitudinal study |
| title_fullStr | Daytime napping, biological aging and cognitive function among middle-aged and older Chinese: insights from the China health and retirement longitudinal study |
| title_full_unstemmed | Daytime napping, biological aging and cognitive function among middle-aged and older Chinese: insights from the China health and retirement longitudinal study |
| title_short | Daytime napping, biological aging and cognitive function among middle-aged and older Chinese: insights from the China health and retirement longitudinal study |
| title_sort | daytime napping biological aging and cognitive function among middle aged and older chinese insights from the china health and retirement longitudinal study |
| topic | cognitive aging Alzheimer’s disease neurodegenerative disease longevity geroscience biological aging |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1294948/full |
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