Sarcoidosis mimicking lymphoma on positron emission tomography-computed tomography in two patients treated for lymphoma: two case reports
<p>Abstract</p> <p>Introduction</p> <p>Sarcoidosis is a granulomatous disease that mostly involves the lungs. Its association with malignancies has been well documented. Several mechanisms have been proposed that may underlie this concurrence including triggering tumour...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-06-01
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| Series: | Journal of Medical Case Reports |
| Online Access: | http://www.jmedicalcasereports.com/content/3/1/7306 |
| _version_ | 1818564874675945472 |
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| author | Ozer Ozden Eskazan Ahmet Emre Ar M Cem Beköz Hüseyin Tabak Fehmi Ongen Gül Ferhanoglu Burhan |
| author_facet | Ozer Ozden Eskazan Ahmet Emre Ar M Cem Beköz Hüseyin Tabak Fehmi Ongen Gül Ferhanoglu Burhan |
| author_sort | Ozer Ozden |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Introduction</p> <p>Sarcoidosis is a granulomatous disease that mostly involves the lungs. Its association with malignancies has been well documented. Several mechanisms have been proposed that may underlie this concurrence including triggering tumour antigens and defective cellular immunity.</p> <p>Case presentations</p> <p>We briefly review the literature on malignancy associated sarcoidosis and report two female lymphoma patients of 49 and 56 years of age who, during their course of disease, developed sarcoidosis that was misinterpreted as a lymphoma relapse on positron emission tomography-computed tomography.</p> <p>Conclusion</p> <p>We hypothesise that T cell dysfunction and exposure to tumour associated antigens might be the underlying mechanisms of development of sarcoidosis in patients with lymphoma. Positron emission tomography-positive lesions do not always indicate malignancy and therefore a tissue biopsy is always mandatory to confirm the diagnosis.</p> |
| first_indexed | 2024-12-14T01:34:13Z |
| format | Article |
| id | doaj.art-ed976227599a4e459fb20d28b5002788 |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-12-14T01:34:13Z |
| publishDate | 2009-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-ed976227599a4e459fb20d28b50027882022-12-21T23:21:57ZengBMCJournal of Medical Case Reports1752-19472009-06-0131730610.4076/1752-1947-3-7306Sarcoidosis mimicking lymphoma on positron emission tomography-computed tomography in two patients treated for lymphoma: two case reportsOzer OzdenEskazan Ahmet EmreAr M CemBeköz HüseyinTabak FehmiOngen GülFerhanoglu Burhan<p>Abstract</p> <p>Introduction</p> <p>Sarcoidosis is a granulomatous disease that mostly involves the lungs. Its association with malignancies has been well documented. Several mechanisms have been proposed that may underlie this concurrence including triggering tumour antigens and defective cellular immunity.</p> <p>Case presentations</p> <p>We briefly review the literature on malignancy associated sarcoidosis and report two female lymphoma patients of 49 and 56 years of age who, during their course of disease, developed sarcoidosis that was misinterpreted as a lymphoma relapse on positron emission tomography-computed tomography.</p> <p>Conclusion</p> <p>We hypothesise that T cell dysfunction and exposure to tumour associated antigens might be the underlying mechanisms of development of sarcoidosis in patients with lymphoma. Positron emission tomography-positive lesions do not always indicate malignancy and therefore a tissue biopsy is always mandatory to confirm the diagnosis.</p>http://www.jmedicalcasereports.com/content/3/1/7306 |
| spellingShingle | Ozer Ozden Eskazan Ahmet Emre Ar M Cem Beköz Hüseyin Tabak Fehmi Ongen Gül Ferhanoglu Burhan Sarcoidosis mimicking lymphoma on positron emission tomography-computed tomography in two patients treated for lymphoma: two case reports Journal of Medical Case Reports |
| title | Sarcoidosis mimicking lymphoma on positron emission tomography-computed tomography in two patients treated for lymphoma: two case reports |
| title_full | Sarcoidosis mimicking lymphoma on positron emission tomography-computed tomography in two patients treated for lymphoma: two case reports |
| title_fullStr | Sarcoidosis mimicking lymphoma on positron emission tomography-computed tomography in two patients treated for lymphoma: two case reports |
| title_full_unstemmed | Sarcoidosis mimicking lymphoma on positron emission tomography-computed tomography in two patients treated for lymphoma: two case reports |
| title_short | Sarcoidosis mimicking lymphoma on positron emission tomography-computed tomography in two patients treated for lymphoma: two case reports |
| title_sort | sarcoidosis mimicking lymphoma on positron emission tomography computed tomography in two patients treated for lymphoma two case reports |
| url | http://www.jmedicalcasereports.com/content/3/1/7306 |
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