Identification of growth hormone receptor as a relevant target for precision medicine in low‐EGFR expressing glioblastoma

Identification of growth hormone receptor as a relevant target for precision medicine in low‐EGFR expressing glioblastoma

Abstract Objective New therapeutic approaches are needed to improve the prognosis of glioblastoma (GBM) patients. Methods With the objective of identifying alternative oncogenic mechanisms to abnormally activated epidermal growth factor receptor (EGFR) signalling, one of the most common oncogenic me...

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Main Authors: Maïté Verreault, Irma Segoviano Vilchis, Shai Rosenberg, Nolwenn Lemaire, Charlotte Schmitt, Jérémy Guehennec, Louis Royer‐Perron, Jean‐Léon Thomas, TuKiet T. Lam, Florent Dingli, Damarys Loew, François Ducray, Sophie Paris, Catherine Carpentier, Yannick Marie, Florence Laigle‐Donadey, Audrey Rousseau, Natascha Pigat, Florence Boutillon, Franck Bielle, Karima Mokhtari, Stuart J. Frank, Aurélien deReyniès, Khê Hoang‐Xuan, Marc Sanson, Vincent Goffin, Ahmed Idbaih
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Clinical and Translational Medicine
Subjects:
cell migration
comparative analysis
glioblastoma
oncogenicity
pre‐clinical models
therapeutic target
Online Access:https://doi.org/10.1002/ctm2.939

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