The Impact of Whey Protein Supplementation on Sarcopenia Progression among the Elderly: A Systematic Review and Meta-Analysis
We conducted a systematic literature review and meta-analysis to investigate the role of whey protein supplementation in the functioning of the elderly with sarcopenia. The aim was to investigate the available scientific evidence and determine the best recommendations with respect to whey protein su...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/9/2039 |
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| author | Magdalena Sylwia Kamińska Kamila Rachubińska Szymon Grochans Karolina Skonieczna-Żydecka Anna Maria Cybulska Elżbieta Grochans Beata Karakiewicz |
| author_facet | Magdalena Sylwia Kamińska Kamila Rachubińska Szymon Grochans Karolina Skonieczna-Żydecka Anna Maria Cybulska Elżbieta Grochans Beata Karakiewicz |
| author_sort | Magdalena Sylwia Kamińska |
| collection | DOAJ |
| description | We conducted a systematic literature review and meta-analysis to investigate the role of whey protein supplementation in the functioning of the elderly with sarcopenia. The aim was to investigate the available scientific evidence and determine the best recommendations with respect to whey protein supplementation in sarcopenic patients. Methods: Databases, including CINAHL, Embase PubMed, and Web of Science, were searched from database inception until 31 December 2022 for randomised controlled trials (RCTs) comparing the efficacy of whey protein supplementation in the elderly with sarcopenia. Data on study design, risk of bias, patient, illness, and treatment characteristics from each study were independently extracted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The tool “assessing risk of bias” from the Cochrane Handbook was used to evaluate the quality of the included papers. Results: The search identified 629 records; 590 articles were excluded as duplicates or after evaluation at the title or abstract level. Out of 39 full-text articles that were reviewed, 29 were excluded for not fulfilling the inclusion criteria. There is some evidence that whey protein supplementation combined with age-appropriate physical exercise might improve muscle mass and lower limb function in the elderly with sarcopenia. The present meta-analysis demonstrated overall that whey supplementation does not improve any of the tested sarcopenia-linked parameters. However, we found that study duration (weeks) and age significantly affect the handgrip strength rate and the chair and stand test rate, respectively, so consideration should be given to oral supplementation combined with the age of participants and an appropriate physical activity as a form of sarcopenia prevention in the high-risk group. |
| first_indexed | 2024-03-11T04:11:41Z |
| format | Article |
| id | doaj.art-eda1176139ae4c5aad8d2721ca702ab8 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-11T04:11:41Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-eda1176139ae4c5aad8d2721ca702ab82023-11-17T23:28:18ZengMDPI AGNutrients2072-66432023-04-01159203910.3390/nu15092039The Impact of Whey Protein Supplementation on Sarcopenia Progression among the Elderly: A Systematic Review and Meta-AnalysisMagdalena Sylwia Kamińska0Kamila Rachubińska1Szymon Grochans2Karolina Skonieczna-Żydecka3Anna Maria Cybulska4Elżbieta Grochans5Beata Karakiewicz6Subdepartment of Long-Term Care and Palliative Medicine, Department of Social Medicine, Faculty of Health Sciences, Pomeranian Medical University in Szczecin, 48 Żołnierska, 71-210 Szczecin, PolandDepartment of Nursing, Faculty of Health Sciences, Pomeranian Medical University in Szczecin, 48 Żołnierska, 71-210 Szczecin, PolandDepartment of Clinical Nursing, Faculty of Health Sciences, Pomeranian Medical University in Szczecin, 48 Żołnierska, 71-210 Szczecin, PolandDepartment of Biochemical Science, Faculty of Health Sciences, Pomeranian Medical University in Szczecin, 24 Broniewskiego, 71-460 Szczecin, PolandDepartment of Nursing, Faculty of Health Sciences, Pomeranian Medical University in Szczecin, 48 Żołnierska, 71-210 Szczecin, PolandDepartment of Nursing, Faculty of Health Sciences, Pomeranian Medical University in Szczecin, 48 Żołnierska, 71-210 Szczecin, PolandSubdepartment of Social Medicine and Public Health, Department of Social Medicine, Faculty of Health Sciences, Pomeranian Medical University in Szczecin, 48 Żołnierska, 71-210 Szczecin, PolandWe conducted a systematic literature review and meta-analysis to investigate the role of whey protein supplementation in the functioning of the elderly with sarcopenia. The aim was to investigate the available scientific evidence and determine the best recommendations with respect to whey protein supplementation in sarcopenic patients. Methods: Databases, including CINAHL, Embase PubMed, and Web of Science, were searched from database inception until 31 December 2022 for randomised controlled trials (RCTs) comparing the efficacy of whey protein supplementation in the elderly with sarcopenia. Data on study design, risk of bias, patient, illness, and treatment characteristics from each study were independently extracted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The tool “assessing risk of bias” from the Cochrane Handbook was used to evaluate the quality of the included papers. Results: The search identified 629 records; 590 articles were excluded as duplicates or after evaluation at the title or abstract level. Out of 39 full-text articles that were reviewed, 29 were excluded for not fulfilling the inclusion criteria. There is some evidence that whey protein supplementation combined with age-appropriate physical exercise might improve muscle mass and lower limb function in the elderly with sarcopenia. The present meta-analysis demonstrated overall that whey supplementation does not improve any of the tested sarcopenia-linked parameters. However, we found that study duration (weeks) and age significantly affect the handgrip strength rate and the chair and stand test rate, respectively, so consideration should be given to oral supplementation combined with the age of participants and an appropriate physical activity as a form of sarcopenia prevention in the high-risk group.https://www.mdpi.com/2072-6643/15/9/2039sarcopeniaolder adultswhey protein |
| spellingShingle | Magdalena Sylwia Kamińska Kamila Rachubińska Szymon Grochans Karolina Skonieczna-Żydecka Anna Maria Cybulska Elżbieta Grochans Beata Karakiewicz The Impact of Whey Protein Supplementation on Sarcopenia Progression among the Elderly: A Systematic Review and Meta-Analysis Nutrients sarcopenia older adults whey protein |
| title | The Impact of Whey Protein Supplementation on Sarcopenia Progression among the Elderly: A Systematic Review and Meta-Analysis |
| title_full | The Impact of Whey Protein Supplementation on Sarcopenia Progression among the Elderly: A Systematic Review and Meta-Analysis |
| title_fullStr | The Impact of Whey Protein Supplementation on Sarcopenia Progression among the Elderly: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | The Impact of Whey Protein Supplementation on Sarcopenia Progression among the Elderly: A Systematic Review and Meta-Analysis |
| title_short | The Impact of Whey Protein Supplementation on Sarcopenia Progression among the Elderly: A Systematic Review and Meta-Analysis |
| title_sort | impact of whey protein supplementation on sarcopenia progression among the elderly a systematic review and meta analysis |
| topic | sarcopenia older adults whey protein |
| url | https://www.mdpi.com/2072-6643/15/9/2039 |
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